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Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12017
TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670419((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670420((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670422((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670423((R)-1-(2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670424((R)-2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670425((R)-2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.200nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670426((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.200nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670421((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 5.60nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM670418((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 12.2nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent