Compile Data Set for Download or QSAR
Report error Found 194 Enz. Inhib. hit(s) with all data for entry = 12012
TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669967(US20240132525, Example 029a)
Affinity DataIC50: 0.0200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670012(US20240132525, Compound C012)
Affinity DataIC50: 0.100nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669954(US20240132525, Example 019)
Affinity DataIC50: 0.200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669958(US20240132525, Example 023)
Affinity DataIC50: 0.200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669966(US20240132525, Example 029)
Affinity DataIC50: 0.200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669993(US20240132525, Example 044a)
Affinity DataIC50: 0.200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670000(US20240132525, Example 050)
Affinity DataIC50: 0.200nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669938(US20240132525, Example 008)
Affinity DataIC50: 0.300nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669979(US20240132525, Example 036a)
Affinity DataIC50: 0.300nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669997(US20240132525, Example 047)
Affinity DataIC50: 0.340nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669944(US20240132525, Example 011a)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669952(US20240132525, Example 017)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669960(US20240132525, Example 025)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669962(US20240132525, Example 026a)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669975(US20240132525, Example 033a)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669989(US20240132525, Example 042a)
Affinity DataIC50: 0.400nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669935(US20240132525, Example 005)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669953(US20240132525, Example 018)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669961(US20240132525, Example 026)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669965(US20240132525, Example 028)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669973(US20240132525, Example 031b)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669995(US20240132525, Example 045 | US20240132525, Exampl...)
Affinity DataIC50: 0.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669941(US20240132525, Example 010a)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669946(US20240132525, Example 012a)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669958(US20240132525, Example 023)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669964(US20240132525, Example 027)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669974(US20240132525, Example 032)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669998(US20240132525, Example 048)
Affinity DataIC50: 0.600nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669931(US20240132525, Example 003)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669932(US20240132525, Example 003a)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669940(US20240132525, Example 010)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669978(US20240132525, Example 035)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670003(US20240132525, Compound C003)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670007(US20240132525, Compound C007)
Affinity DataIC50: 0.700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669987(US20240132525, Example 041a)
Affinity DataIC50: 0.800nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669993(US20240132525, Example 044a)
Affinity DataIC50: 0.800nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670015(US20240132525, Compound C015)
Affinity DataIC50: 0.800nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669930(US20240132525, Example 002)
Affinity DataIC50: 0.900nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669943(US20240132525, Example 011)
Affinity DataIC50: 0.900nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669991(US20240132525, Example 043a)
Affinity DataIC50: 0.900nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669936(US20240132525, Example 006)
Affinity DataIC50: 1nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669925(US20240132525, Example 001)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669939(US20240132525, Example 009)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669977(US20240132525, Example 034)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669983(US20240132525, Example 039a)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669986(US20240132525, Example 040b)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670002(US20240132525, Compound C002)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670004(US20240132525, Compound C004)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM670005(US20240132525, Compound C005)
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Boehringer Ingelheim Animal Health Usa

US Patent
LigandPNGBDBM669971(US20240132525, Example 031)
Affinity DataIC50: 1.20nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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