Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 12009
TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669885(US20240132514, Example 2 | 2-({5H,6H,8H-pyrano[3,4...)
Affinity DataIC50: 60nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669885(US20240132514, Example 2 | 2-({5H,6H,8H-pyrano[3,4...)
Affinity DataIC50: 105nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669886(US20240132514, Example 3 | 2-{[6- (hydroxymethyl)p...)
Affinity DataIC50: 340nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669887(US20240132514, Example 24 | 2-{[6- (methoxymethyl)...)
Affinity DataIC50: 725nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669886(US20240132514, Example 3 | 2-{[6- (hydroxymethyl)p...)
Affinity DataKi:  340nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent