Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 11920
TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661044(US20240101538, Compound 95b | US20240101538, Compo...)
Affinity DataIC50: 7.90nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661047(US20240101538, Compound 2c | N-(5-((4-(1H-pyrazole...)
Affinity DataIC50: 27.6nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661046(US20240101538, Compound 97 | N-(2-fluoro-5-((4-(1-...)
Affinity DataIC50: 532nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661044(US20240101538, Compound 95b | US20240101538, Compo...)
Affinity DataIC50: 6.90E+3nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661043(US20240101538, Compound 18c | N-(5-(((4-(1H-Pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661048(US20240101538, Compound 3a | N-(2-fluoro-5-((4-(1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661049(US20240101538, Compound 107n | N-(2-fluoro-5-((4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661050(US20240101538, Compound 107o | N-(2-fluoro-5-((4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661051(US20240101538, Compound 107p | N-(2-fluoro-5-((4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661052(US20240101538, Compound 107r | (E)-N-(2-fluoro-5-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661053(US20240101538, Compound 107s | N-(2-fluoro-5-((4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent