Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 11871
TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  37.4nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  51.8nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Mouse)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  134nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Rat)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  146nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655986(US20240067633, Isomer 2 of compound 4)
Affinity DataEC50:  19.4nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  36.5nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  35.2nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  58.6nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  59.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655989(2-((1R,5S,6R)-3-(7,7-difluoro-2-((S)-2-(methyl-d3)...)
Affinity DataEC50:  37.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655990((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-(methyl-d3)aze...)
Affinity DataEC50:  52.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655991(US20240067633, Isomer 2 of compound 19)
Affinity DataEC50:  60.6nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655992(US20240067633, Isomer 2 of compound 20)
Affinity DataEC50:  49.8nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655993(US20240067633, Compound Control)
Affinity DataEC50:  123nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent