Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 11829
TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651804(US20240051954, Example 16 | 5-(6-chloro-5-methoxy-...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651803(US20240051954, Example 15 | 6-chloro-2-(5-(1,1-dif...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651791(US20240051954, Example 3 | 6-chloro-2-(5-(1,1-difl...)
Affinity DataIC50: 32nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651815(US20240051954, Example 27 | 2-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 45nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651822(US20240051954, Example 34 | 2-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 54nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651796(US20240051954, Example 8 | 6-chloro-2-(5-(1,1-difl...)
Affinity DataIC50: 55nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651816(US20240051954, Example 28 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 61nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651798(US20240051954, Example 10 | 6-chloro-2-(5-fluoro-4...)
Affinity DataIC50: 63nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651794(US20240051954, Example 6 | 1-(5-(6-chloro-5-methox...)
Affinity DataIC50: 66nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651830(US20240051954, Example 42 | 1-(5-(6-chloro-5-metho...)
Affinity DataIC50: 66nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651829(US20240051954, Example 41 | 6-chloro-5-methoxy-1-m...)
Affinity DataIC50: 67nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651789(US20240051954, Example 1 | 6-chloro-5-methoxy-1-me...)
Affinity DataIC50: 76nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651832(US20240051954, Example 44 | 6-chloro-2-(5-(1,2-dim...)
Affinity DataIC50: 77nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651819(US20240051954, Example 31 | 6-chloro-2-(5-(1,1-dif...)
Affinity DataIC50: 79nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651834(US20240051954, Example 46 | 6-chloro-3-(1H-imidazo...)
Affinity DataIC50: 80nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651835(US20240051954, Example 47 | 6-chloro-5-methoxy-3-(...)
Affinity DataIC50: 91nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651810(US20240051954, Example 22 | 6-chloro-2-(5-(2,2-dif...)
Affinity DataIC50: 93nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651793(US20240051954, Example 5 | 2-(5-(6-chloro-5-methox...)
Affinity DataIC50: 97nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651831(US20240051954, Example 43 | 5-(6-chloro-5-methoxy-...)
Affinity DataIC50: 98nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651828(US20240051954, Example 40 | (E)-1-(5-(6-chloro-3-(...)
Affinity DataIC50: 101nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651814(US20240051954, Example 26 | 6-chloro-3-(1H-imidazo...)
Affinity DataIC50: 107nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651812(US20240051954, Example 24 | 2-(1-(5-(6-chloro-3-(1...)
Affinity DataIC50: 114nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651805(US20240051954, Example 17 | 5-(6-chloro-3-(1H-imid...)
Affinity DataIC50: 116nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651809(US20240051954, Example 21 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 121nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651801(US20240051954, Example 13 | 6-chloro-2-(5-chloro-4...)
Affinity DataIC50: 122nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651825(US20240051954, Example 37 | 1-(5-(6-chloro-5-metho...)
Affinity DataIC50: 123nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651790(US20240051954, Example 2 | 6-chloro-2-(5-(1,1-difl...)
Affinity DataIC50: 124nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651811(US20240051954, Example 23 | 6-chloro-2-(5-(1,2-dim...)
Affinity DataIC50: 144nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651799(US20240051954, Example 11 | 6-chloro-5-methoxy-2-(...)
Affinity DataIC50: 155nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651818(US20240051954, Example 30 | 6-chloro-2-(5-(1,1-dif...)
Affinity DataIC50: 186nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651820(US20240051954, Example 32 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 188nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651827(US20240051954, Example 39 | (E)-1-(5-(6-chloro-3-(...)
Affinity DataIC50: 252nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651806(US20240051954, Example 18 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 258nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651797(US20240051954, Example 9 | 6-chloro-2-(5-fluoro-4H...)
Affinity DataIC50: 267nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651807(US20240051954, Example 19 | 5-(6-chloro-3-(1H-imid...)
Affinity DataIC50: 289nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651837(US20240051954, Example 49 | 6-chloro-3-(1H-pyrazol...)
Affinity DataIC50: 294nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651817(US20240051954, Example 29 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 295nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651839(US20240051954, Example 51 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 308nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651821(US20240051954, Example 33 | 6-chloro-2-(5-fluoro-4...)
Affinity DataIC50: 332nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651800(US20240051954, Example 12 | 6-chloro-5-methoxy-2-(...)
Affinity DataIC50: 333nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651826(US20240051954, Example 38 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 335nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651792(US20240051954, Example 4 | 6-chloro-2-(5-(fluorome...)
Affinity DataIC50: 335nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651813(US20240051954, Example 25 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 369nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651833(US20240051954, Example 45 | 6-chloro-3-(1H-imidazo...)
Affinity DataIC50: 384nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651824(US20240051954, Example 36 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 454nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651838(US20240051954, Example 50 | 6-chloro-1-methyl-3-(1...)
Affinity DataIC50: 741nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651795(US20240051954, Example 7 | (5-(6-chloro-5-methoxy-...)
Affinity DataIC50: 756nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651808(US20240051954, Example 20 | 5-(6-chloro-3-(1H-imid...)
Affinity DataIC50: 824nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651802(US20240051954, Example 14 | 6-chloro-5-methoxy-1-m...)
Affinity DataIC50: 3.52E+3nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651823(US20240051954, Example 35 | 6-chloro-3-(1H-imidazo...)
Affinity DataIC50: 4.07E+3nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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