Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11824
Target72 kDa type IV collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 0.240nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetMatrix metalloproteinase-9(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 0.300nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

Target72 kDa type IV collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 2.70nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetMatrix metalloproteinase-9(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 5nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetInterstitial collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 120nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetInterstitial collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 860nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent