Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 11815
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649901(US20240043405, Compound 027)
Affinity DataIC50: 6.37nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649909(US20240043405, Compound 038)
Affinity DataIC50: 12.1nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649902(US20240043405, Compound 028)
Affinity DataIC50: 12.5nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649894(US20240043405, Compound 006)
Affinity DataIC50: 14nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649910(US20240043405, Compound 039)
Affinity DataIC50: 14.9nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649896(US20240043405, Compound 013)
Affinity DataIC50: 18.5nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649899(US20240043405, Compound 025)
Affinity DataIC50: 26.6nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649905(US20240043405, Compound 031)
Affinity DataIC50: 40.1nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649900(US20240043405, Compound 026)
Affinity DataIC50: 68.1nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649907(US20240043405, Compound 033)
Affinity DataIC50: 74.2nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649890(US20240043405, Compound 001)
Affinity DataIC50: 129nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649895(US20240043405, Compound 007)
Affinity DataIC50: 150nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649893(US20240043405, Compound 005)
Affinity DataIC50: 189nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649891(US20240043405, Compound 002)
Affinity DataIC50: 257nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649897(US20240043405, Compound 016)
Affinity DataIC50: 301nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649908(US20240043405, Compound 034)
Affinity DataIC50: 344nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649904(US20240043405, Compound 030)
Affinity DataIC50: 399nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649898(US20240043405, Compound 024)
Affinity DataIC50: 612nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649903(US20240043405, Compound 029)
Affinity DataIC50: 658nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649892(US20240043405, Compound 003)
Affinity DataIC50: 671nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649902(US20240043405, Compound 028)
Affinity DataIC50: 722nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649905(US20240043405, Compound 031)
Affinity DataIC50: 1.11E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649906(US20240043405, Compound 032)
Affinity DataIC50: 1.19E+3nMAssay Description:To measure the IC50 values of the compounds herein against IRAK1, the Adapta Universal Kinase Assay (ThermoFisher) was used. Briefly, 100 nL of diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649899(US20240043405, Compound 025)
Affinity DataIC50: 1.63E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649901(US20240043405, Compound 027)
Affinity DataIC50: 1.87E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649908(US20240043405, Compound 034)
Affinity DataIC50: 2.01E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649907(US20240043405, Compound 033)
Affinity DataIC50: 2.51E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649898(US20240043405, Compound 024)
Affinity DataIC50: 3.33E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649904(US20240043405, Compound 030)
Affinity DataIC50: 3.33E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649894(US20240043405, Compound 006)
Affinity DataIC50: 4.00E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649897(US20240043405, Compound 016)
Affinity DataIC50: 9.93E+3nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649900(US20240043405, Compound 026)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649909(US20240043405, Compound 038)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649910(US20240043405, Compound 039)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649906(US20240043405, Compound 032)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649903(US20240043405, Compound 029)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649896(US20240043405, Compound 013)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649895(US20240043405, Compound 007)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649893(US20240043405, Compound 005)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649892(US20240043405, Compound 003)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649891(US20240043405, Compound 002)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM649890(US20240043405, Compound 001)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the IC50 values of compounds herein against IRAK4, a Z′-LYTE assay (ThermoFisher) was used. Briefly, 2.5 μL. of different conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent