Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 9605
TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649657(US20240041837, Example 30)
Affinity DataIC50: 36nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 48nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 58nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 58nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649656(US20240041837, Example 29)
Affinity DataIC50: 59nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649648(US20240041837, Example 22)
Affinity DataIC50: 64nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649633(US20240041837, Example 7)
Affinity DataIC50: 77nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649643(US20240041837, Example 17)
Affinity DataIC50: 83nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649631(US20240041837, Example 4)
Affinity DataIC50: 110nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649645(US20240041837, Example 19)
Affinity DataIC50: 119nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649641(US20240041837, Example 15)
Affinity DataIC50: 122nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649632(US20240041837, Example 5)
Affinity DataIC50: 137nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649654(US20240041837, Example 28)
Affinity DataIC50: 140nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649642(US20240041837, Example 16)
Affinity DataIC50: 141nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649639(US20240041837, Example 13)
Affinity DataIC50: 197nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649636(US20240041837, Example 10)
Affinity DataIC50: 211nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649640(US20240041837, Example 14)
Affinity DataIC50: 234nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649638(US20240041837, Example 12)
Affinity DataIC50: 302nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649629(US20240041837, Example 2)
Affinity DataIC50: 324nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649628(US20240041837, Example 1)
Affinity DataIC50: 346nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649634(US20240041837, Example 8)
Affinity DataIC50: 487nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649635(US20240041837, Example 9)
Affinity DataIC50: 548nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649647(US20240041837, Example 21)
Affinity DataIC50: 610nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649649(US20240041837, Example 23)
Affinity DataIC50: 659nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649644(US20240041837, Example 18)
Affinity DataIC50: 750nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649646(US20240041837, Example 20)
Affinity DataIC50: 896nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649652(US20240041837, Example 26)
Affinity DataIC50: 1.24E+3nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649630(US20240041837, Example 3)
Affinity DataIC50: 1.33E+3nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649651(US20240041837, Example 25)
Affinity DataIC50: 2.29E+3nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649650(US20240041837, Example 24)
Affinity DataIC50: 2.53E+3nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM649653(US20240041837, Example 27)
Affinity DataIC50: 3.43E+3nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.33E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetGlucocorticoid receptor(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.82E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetEstrogen receptor beta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.94E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetThyroid hormone receptor beta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 3.08E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor gamma(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 3.98E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent