Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 11799
TargetReplicase polyprotein 1ab(HCoV-OC43)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1 | US1216...)
Affinity DataEC50:  12nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1 | US1216...)
Affinity DataEC50:  63nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM430624(NHC | EIDD-1931 | N4-Hydroxycytidine | Uridine, 4-...)
Affinity DataEC50:  300nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  35nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  147nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  770nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataEC50:  22nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataEC50:  43nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataEC50:  200nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1 | US1216...)
Affinity DataEC50:  22nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM648846(US20240034730, Compound 41)
Affinity DataIC50: 0.820nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281167(CHEMBL4175712 | US20240034730, Compound 38 | US121...)
Affinity DataIC50: 1nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1 | US1216...)
Affinity DataIC50: 1.20nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586377(CHEMBL5086254 | US20240034730, Compound 7)
Affinity DataIC50: 1.35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM648845(US20240034730, Compound 40)
Affinity DataIC50: 1.48nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 1.80nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586381(CHEMBL5092556 | US20240034730, Compound 11)
Affinity DataIC50: 2.03nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586385(CHEMBL5090431 | US20240034730, Compound 15)
Affinity DataIC50: 2.30nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM648848(US20240034730, Compound 43)
Affinity DataIC50: 2.5nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586386(CHEMBL5084878 | US20240034730, Compound 16)
Affinity DataIC50: 2.75nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586384(CHEMBL5088148 | US20240034730, Compound 14)
Affinity DataIC50: 2.78nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM648847(US20240034730, Compound 42)
Affinity DataIC50: 3.29nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586374(CHEMBL5075870 | US20240034730, Compound 4)
Affinity DataIC50: 3.40nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586387(CHEMBL5090281 | US20240034730, Compound 17)
Affinity DataIC50: 4.09nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281170(CHEMBL4165923 | US20240034730, Compound 2 | US1216...)
Affinity DataIC50: 4.30nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586375(CHEMBL5087682 | US20240034730, Compound 5)
Affinity DataIC50: 5.80nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM470454(N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxym...)
Affinity DataIC50: 6nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586378(CHEMBL5079607 | US20240034730, Compound 8)
Affinity DataIC50: 6.23nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586383(CHEMBL5078949 | US20240034730, Compound 13)
Affinity DataIC50: 6.34nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591141(CHEMBL5192490 | US20240034730, Compound 29)
Affinity DataIC50: 7.20nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM648831(US20240034730, Compound 25)
Affinity DataIC50: 13nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586380(CHEMBL5071607 | US20240034730, Compound 10)
Affinity DataIC50: 17.7nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591156(CHEMBL5196292 | US20240034730, Compound 37)
Affinity DataIC50: 18nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3 | US1216...)
Affinity DataIC50: 35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM119812(US8691852, 20 | US20240034730, Compound ASLAN003)
Affinity DataIC50: 35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281172(CHEMBL4165815 | US20240034730, Compound 18)
Affinity DataIC50: 43nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591155(CHEMBL5183718 | US20240034730, Compound 36)
Affinity DataIC50: 70nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586382(CHEMBL5079952 | US20240034730, Compound 12)
Affinity DataIC50: 71.8nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586376(CHEMBL5090397 | US20240034730, Compound 6)
Affinity DataIC50: 90.9nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591142(CHEMBL5209405 | US20240034730, Compound 30)
Affinity DataIC50: 114nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50586379(CHEMBL5080170 | US20240034730, Compound 9)
Affinity DataIC50: 150nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591140(CHEMBL5182435 | US20240034730, Compound 28)
Affinity DataIC50: 400nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50281168(CHEMBL4167855 | US20240034730, Compound 27 | US121...)
Affinity DataIC50: 480nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591154(CHEMBL5181901 | US20240034730, Compound 26)
Affinity DataIC50: 2.21E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591146(CHEMBL5190641 | US20240034730, Compound 34)
Affinity DataIC50: 2.21E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591149(CHEMBL5172821 | US20240034730, Compound 20)
Affinity DataIC50: 2.76E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591145(CHEMBL5178813 | US20240034730, Compound 33)
Affinity DataIC50: 3.94E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591143(CHEMBL5173387 | US20240034730, Compound 31)
Affinity DataIC50: 5.20E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591147(CHEMBL5193995 | US20240034730, Compound 35)
Affinity DataIC50: 6.98E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591151(CHEMBL5188838 | US20240034730, Compound 22)
Affinity DataIC50: 7.20E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

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