Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 11774
TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646010((2S,4R)-4-hydroxy-1-((2S)-2-(2-(2-(2- hydroxypheny...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTranscription activator BRG1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646010((2S,4R)-4-hydroxy-1-((2S)-2-(2-(2-(2- hydroxypheny...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646012(US20240018158, Example 2b | (2S,4R)-4-hydroxy-N-[[...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTranscription activator BRG1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646012(US20240018158, Example 2b | (2S,4R)-4-hydroxy-N-[[...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646014((2S,4R)-4-hydroxy-1-((2S)-2-(2-(4-((2-(2- hydroxyp...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646015((2S,4R)-4-hydroxy-1-((2R)-2-(3-(2-(2-(2- hydroxyph...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646016((2S,4R)-4-hydroxy-1-((2S)-2-(3-(2-(4-((2-(2- hydro...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646010((2S,4R)-4-hydroxy-1-((2S)-2-(2-(2-(2- hydroxypheny...)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetProbable global transcription activator SNF2L2(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646012(US20240018158, Example 2b | (2S,4R)-4-hydroxy-N-[[...)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTranscription activator BRG1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM646012(US20240018158, Example 2b | (2S,4R)-4-hydroxy-N-[[...)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent