Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 11716
TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642519(US20230414581, Compound 2)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50542876(CHEMBL4647174 | US20230414581, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642521(US20230414581, Compound 4)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642523(US20230414581, Compound 5)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50384774(CHEMBL1917204 | US20230414581, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | med.21724, Compou...)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642528(US20230414581, Compound 8)
Affinity DataIC50: 5.50E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50365735(MKT-077 | CHEMBL33859 | US20230414581, Compound 39)
Affinity DataIC50: 5.50E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642529(US20230414581, Compound 32)
Affinity DataIC50: 1.00E+4nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 1.00E+4nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM642531(US20230414581, Compound 36)
Affinity DataIC50: 1.00E+4nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 1.00E+4nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent