Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 11656
TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636863(US20230382870, Compound of Example 24)
Affinity DataIC50: 68nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636861(US20230382870, Compound of Example 22)
Affinity DataIC50: 73nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636865(US20230382870, Compound of Example 26)
Affinity DataIC50: 75nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636869(US20230382870, Compound of Example 30)
Affinity DataIC50: 88nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636864(US20230382870, Compound of Example 25)
Affinity DataIC50: 91nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636868(US20230382870, Compound of Example 29)
Affinity DataIC50: 105nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636860(US20230382870, Compound of Example 20)
Affinity DataIC50: 107nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636862(US20230382870, Compound of Example 23)
Affinity DataIC50: 115nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636858(US20230382870, Compound of Example 17)
Affinity DataIC50: 116nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636856(US20230382870, Compound of Example 15)
Affinity DataIC50: 125nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636866(US20230382870, Compound of Example 27)
Affinity DataIC50: 133nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636857(US20230382870, Compound of Example 16)
Affinity DataIC50: 147nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636867(US20230382870, Compound of Example 28)
Affinity DataIC50: 159nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636859(US20230382870, Compound of Example 18)
Affinity DataIC50: 168nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636853(US20230382870, Compound of Example 12)
Affinity DataIC50: 205nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636844(US20230382870, Compound of Example 3)
Affinity DataIC50: 215nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 218nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636846(US20230382870, Compound of Example 5)
Affinity DataIC50: 227nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636850(US20230382870, Compound of Example 9)
Affinity DataIC50: 232nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636845(US20230382870, Compound of Example 4)
Affinity DataIC50: 246nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636848(US20230382870, Compound of Example 7)
Affinity DataIC50: 253nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636847(US20230382870, Compound of Example 6)
Affinity DataIC50: 261nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM18678(CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataIC50: 264nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636843(US20230382870, Compound of Example 2)
Affinity DataIC50: 337nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636849(US20230382870, Compound of Example 8)
Affinity DataIC50: 357nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636854(US20230382870, Compound of Example 13)
Affinity DataIC50: 416nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636851(US20230382870, Compound of Example 10)
Affinity DataIC50: 437nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636852(US20230382870, Compound of Example 11)
Affinity DataIC50: 505nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636842(US20230382870, Compound of Example 1)
Affinity DataIC50: 546nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 637nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636855(US20230382870, Compound of Example 14)
Affinity DataIC50: 760nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636848(US20230382870, Compound of Example 7)
Affinity DataKi:  295nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636846(US20230382870, Compound of Example 5)
Affinity DataKi:  314nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636853(US20230382870, Compound of Example 12)
Affinity DataKi:  351nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636844(US20230382870, Compound of Example 3)
Affinity DataKi:  367nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636851(US20230382870, Compound of Example 10)
Affinity DataKi:  387nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636847(US20230382870, Compound of Example 6)
Affinity DataKi:  421nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636849(US20230382870, Compound of Example 8)
Affinity DataKi:  440nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636850(US20230382870, Compound of Example 9)
Affinity DataKi:  445nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636845(US20230382870, Compound of Example 4)
Affinity DataKi:  491nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM636852(US20230382870, Compound of Example 11)
Affinity DataKi:  505nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM18678(CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataKi:  518nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  1.25E+3nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Shenzhen Edk Pharmaceutical Technology

US Patent
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataKi:  2.75E+3nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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