Compile Data Set for Download or QSAR
Report error Found 200 Enz. Inhib. hit(s) with all data for entry = 11589
TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629510(US20230339981, Example 198)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629513(US20230339981, Example 201)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629509(US20230339981, Example 197)
Affinity DataIC50: 0.0400nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629518(US20230339981, Example 206)
Affinity DataIC50: 0.0400nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629381(US20230339981, Example 68)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629505(US20230339981, Example 193)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629512(US20230339981, Example 200)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629387(US20230339981, Example 75)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629517(US20230339981, Example 205)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629519(US20230339981, Example 207)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629507(US20230339981, Example 195)
Affinity DataIC50: 0.0700nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629511(US20230339981, Example 199)
Affinity DataIC50: 0.0700nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629380(US20230339981, Example 67)
Affinity DataIC50: 0.0800nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629520(US20230339981, Example 208)
Affinity DataIC50: 0.0900nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629340(US20230339981, Example 22)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629368(US20230339981, Example 52)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629369(US20240025919, Compound 7 | US20230339981, Example...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629377(US20230339981, Example 64)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629382(US20230339981, Example 69)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629383(US20230339981, Example 70)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629388(US20230339981, Example 76)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629392(US20230339981, Example 80 | US20230339981, Example...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629406(US20230339981, Example 94)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629421(US20230339981, Example 109)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629427(US20230339981, Example 115)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629429(US20230339981, Example 117)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629434(US20230339981, Example 122)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629435(US20230339981, Example 123)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629445(US20230339981, Example 133)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629451(US20230339981, Example 139)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629422(US20230339981, Example 110 | US20230339981, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629460(US20230339981, Example 148)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629461(US20230339981, Example 149)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629463(US20230339981, Example 151 | US20230339981, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629464(US20230339981, Example 152)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629466(US20230339981, Example 154)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629467(US20230339981, Example 155)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629475(US20230339981, Example 163)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629477(US20230339981, Example 165)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629479(US20230339981, Example 167)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629483(US20230339981, Example 171)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629485(US20230339981, Example 173)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629488(US20230339981, Example 176)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629489(US20230339981, Example 177)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629491(US20230339981, Example 179)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629501(US20230339981, Example 189)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629502(US20230339981, Example 190)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629504(US20230339981, Example 192)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629508(US20230339981, Example 196)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629516(US20230339981, Example 204)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

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