Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 11544
TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625397(US20230322788, Compound B1)
Affinity DataIC50: 6.20nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625392(US20230322788, Compound A19)
Affinity DataIC50: 9.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625398(US20230322788, Compound B2)
Affinity DataIC50: 13nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625393(US20230322788, Compound A20)
Affinity DataIC50: 19.1nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625399(US20230322788, Compound B3)
Affinity DataIC50: 20.3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625394(US20230322788, Compound A21)
Affinity DataIC50: 20.8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625378(US20230322788, Compound A5)
Affinity DataIC50: 29nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625377(US20230322788, Compound A4)
Affinity DataIC50: 46.7nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625380(US20230322788, Compound A7)
Affinity DataIC50: 47.8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625401(US20230322788, Compound B5)
Affinity DataIC50: 64.1nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625379(US20230322788, Compound A6)
Affinity DataIC50: 100nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625386(US20230322788, Compound A13)
Affinity DataIC50: 101nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625383(US20230322788, Compound A10)
Affinity DataIC50: 187nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625395(US20230322788, Compound A22)
Affinity DataIC50: 201nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625384(US20230322788, Compound A11)
Affinity DataIC50: 215nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625385(US20230322788, Compound A12)
Affinity DataIC50: 217nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625391(US20230322788, Compound A18)
Affinity DataIC50: 235nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625400(US20230322788, Compound B4)
Affinity DataIC50: 329nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625375(US20230322788, Compound A2)
Affinity DataIC50: 427nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625396(US20230322788, Compound A23)
Affinity DataIC50: 489nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625387(US20230322788, Compound A14)
Affinity DataIC50: 506nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625402(US20230322788, Compound B6)
Affinity DataIC50: 639nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625382(US20230322788, Compound A9)
Affinity DataIC50: 1.06E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625388(US20230322788, Compound A15)
Affinity DataIC50: 1.18E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625390(US20230322788, Compound A17)
Affinity DataIC50: 2.93E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625374(US20230322788, Compound A1)
Affinity DataIC50: 3.28E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625381(US20230322788, Compound A8)
Affinity DataIC50: 7.70E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625389(US20230322788, Compound A16)
Affinity DataIC50: 1.00E+4nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625376(US20230322788, Compound A3)
Affinity DataIC50: 1.00E+4nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent