Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11440
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM616829(US20230279001, Example 4 | 1-[5-(2,8-dimethylimida...)
Affinity DataIC50: 1.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM616830(US20230279001, Example 15 | (3R,4R)-1-[1-[6-ethyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM616831(US20230279001, Example 20 | 1-[5-(2,8-dimethylimid...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM616832(US20230279001, Example 25 | 6-[2-methoxy-6-(4-pipe...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent