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Found
21
Enz. Inhib. hit(s) with all data for entry = 12895
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524247
(CHEMBL4537738 | US12297164, Example 4)
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Affinity Data
Kd: 780nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524248
(CHEMBL4439690 | US12297164, Example 2)
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Affinity Data
Kd: 380nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524231
(CHEMBL4558865 | US12297164, Example 1)
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Affinity Data
Kd: 560nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524248
(CHEMBL4439690 | US12297164, Example 2)
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Copy InChI
Affinity Data
IC50: 30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524231
(CHEMBL4558865 | US12297164, Example 1)
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Copy InChI
Affinity Data
IC50: 120nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524247
(CHEMBL4537738 | US12297164, Example 4)
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Affinity Data
IC50: 190nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM738193
(Positive inhibitor UA | US12297164, Example 9)
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Affinity Data
IC50: 680nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524248
(CHEMBL4439690 | US12297164, Example 2)
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Affinity Data
IC50: 750nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM738179
(Compound prepared in Example 6 | US12297164, Examp...)
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Affinity Data
IC50: 960nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524239
(CHEMBL4469780 | US12297164, Example 3)
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Affinity Data
IC50: 1.49E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Go to US Patent
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM26063
([3H]T0901317 | US12297164, Example 8)
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Affinity Data
IC50: 1.70E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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PDB
3D Structure (crystal)
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524231
(CHEMBL4558865 | US12297164, Example 1)
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Affinity Data
IC50: 2.28E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM26063
([3H]T0901317 | US12297164, Example 8)
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Affinity Data
IC50: 2.50E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
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Go to US Patent
PDB
3D Structure (crystal)
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Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524240
(CHEMBL4462547 | US12297164, Example 5)
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Affinity Data
IC50: 2.68E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524247
(CHEMBL4537738 | US12297164, Example 4)
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Affinity Data
IC50: 3.46E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524240
(CHEMBL4462547 | US12297164, Example 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.16E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524242
(CHEMBL4441703 | US12297164, Example 7)
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Affinity Data
IC50: 4.17E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524239
(CHEMBL4469780 | US12297164, Example 3)
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Affinity Data
IC50: 4.85E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM738179
(Compound prepared in Example 6 | US12297164, Examp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.17E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM738193
(Positive inhibitor UA | US12297164, Example 9)
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Affinity Data
IC50: 9.41E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Nuclear receptor ROR-gamma
(Human)
Guangzhou IMD Therapeutics Co.
US Patent
Ligand
BDBM50524242
(CHEMBL4441703 | US12297164, Example 7)
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Affinity Data
IC50: 1.02E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/11/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL