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Found
7
Enz. Inhib. hit(s) with all data for entry = 12808
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729834
(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)
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Affinity Data
IC50: 6.20nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
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Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729840
(2-(5-((6-(6-amino-5-methylpyrazin-2-yl)imidazo[1,2...)
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Affinity Data
IC50: 8.70nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729838
(2-(5-((6-(6-aminopyrazin-2-yl)imidazo[1,2-a]pyrazi...)
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Affinity Data
IC50: 12.2nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729836
((R)-(4-(4-((6-(6-aminopyrazin-2-yl)imidazo[1,2-a]p...)
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Affinity Data
IC50: 13.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729835
(6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piper...)
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Affinity Data
IC50: 13.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729839
(2-((4-(4-((6-(6-aminopyrazin-2-yl)imidazo[1,2-a]py...)
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Copy InChI
Affinity Data
IC50: 14.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase SYK
(Human)
Kronos Bio
US Patent
Ligand
BDBM729837
(6-(6-aminopyrazin-2-yl)-5-methyl-N-(4-(4-(oxetan-3...)
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Affinity Data
IC50: 44nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL