Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 12727
TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723429(US12234230, Compound 42)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723436(US12234230, Compound 49)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723435(US12234230, Compound 48)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723434(US12234230, Compound 47)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723433(US12234230, Compound 46)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723410(US12234230, Compound 23)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723432(US12234230, Compound 45)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723431(US12234230, Compound 44)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723430(US12234230, Compound 43)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723437(US12234230, Compound 50)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723428(US12234230, Compound 41)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723427(US12234230, Compound 40)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723426(US12234230, Compound 39)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723425(US12234230, Compound 38)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723388(US12234230, Compound 1)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723424(US12234230, Compound 37)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723423(US12234230, Compound 36)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723422(US12234230, Compound 35)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723404(US12234230, Compound 17)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723390(US12234230, Compound 3)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723391(US12234230, Compound 4)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723429(US12234230, Compound 42)
Affinity DataIC50: 5nMAssay Description:Table 11-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723410(US12234230, Compound 23)
Affinity DataIC50: 5nMAssay Description:Table 11-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723390(US12234230, Compound 3)
Affinity DataIC50: 5nMAssay Description:Table 11-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723429(US12234230, Compound 42)
Affinity DataIC50: 5nMAssay Description:Table 8-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723410(US12234230, Compound 23)
Affinity DataIC50: 5nMAssay Description:Table 8-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723390(US12234230, Compound 3)
Affinity DataIC50: 5nMAssay Description:Table 8-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723440(US12234230, Compound 53)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723439(US12234230, Compound 52)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723438(US12234230, Compound 51)
Affinity DataIC50: 5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723425(US12234230, Compound 38)
Affinity DataIC50: 27.5nMAssay Description:Table 8-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723404(US12234230, Compound 17)
Affinity DataIC50: 27.5nMAssay Description:Table 8-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723425(US12234230, Compound 38)
Affinity DataIC50: 27.5nMAssay Description:Table 11-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723419(US12234230, Compound 32)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723404(US12234230, Compound 17)
Affinity DataIC50: 27.5nMAssay Description:Table 11-1: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL. Cbl-b displacement assays were performed in a 384-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723420(US12234230, Compound 33)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723402(US12234230, Compound 15)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723395(US12234230, Compound 8)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723421(US12234230, Compound 34)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723412(US12234230, Compound 25)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723413(US12234230, Compound 26)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723414(US12234230, Compound 27)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723415(US12234230, Compound 28)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723416(US12234230, Compound 29)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723417(US12234230, Compound 30)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723418(US12234230, Compound 31)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723394(US12234230, Compound 7)
Affinity DataIC50: 65nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723396(US12234230, Compound 9)
Affinity DataIC50: 65nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723397(US12234230, Compound 10)
Affinity DataIC50: 65nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723398(US12234230, Compound 11)
Affinity DataIC50: 65nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent

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