Compile Data Set for Download or QSAR
Report error Found 1027 Enz. Inhib. hit(s) with all data for entry = 12673
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565417(US11414431, Compound I-1 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565436(US11414431, Compound I-2 | US12221453, Compound I-...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565437(US11414431, Compound I-3 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565438(US11414431, Compound I-4 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565439(US11414431, Compound I-5 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565440(US11414431, Compound I-6 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565441(US11414431, Compound I-7 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565442(US11414431, Compound I-8 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565443(US11414431, Compound I-9 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM423689(US10508120, Compound I-144 | US10577373, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565445(US11414431, Compound I-11 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424635(US10508120, Compound I-1090 | US10577373, Compound...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565447(US11414431, Compound I-13 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565448(US11414431, Compound I-14 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424754(US10508120, Compound I-1258 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565450(US11414431, Compound I-16 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565451(US11414431, Compound I-17 | US12221453, Compound I...)
Affinity DataKd:  5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424810(US10508120, Compound I-1314 | US10577373, Compound...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565453(US11414431, Compound I-19 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424710(US10508120, Compound I-1214 | US10577373, Compound...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565455(US11414431, Compound I-21 | US12221453, Compound I...)
Affinity DataKd:  5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424709(US10508120, Compound I-1213 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565457(US11414431, Compound I-23 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565458(US11414431, Compound I-24 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565459(US11414431, Compound I-25 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565460(US11414431, Compound I-26 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565461(US11414431, Compound I-27 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565462(US11414431, Compound I-28 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565463(US11414431, Compound I-29 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565464(US11414431, Compound I-30 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565465(US11414431, Compound I-31 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565466(US11414431, Compound I-32 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565467(US11414431, Compound I-33 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565468(US11414431, Compound I-34 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565469(US11414431, Compound I-35 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424708(US10508120, Compound I-1212 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565471(US11414431, Compound I-37 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565472(US11414431, Compound I-38 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565473(US11414431, Compound I-39 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424707(US10508120, Compound I-1211 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565475(US11414431, Compound I-41 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424699(US10508120, Compound I-1203 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565477(US11414431, Compound I-43 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424698(US10508120, Compound I-1202 | US10577373, Compound...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565479(US11414431, Compound I-45 | US12221453, Compound I...)
Affinity DataKd:  0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565480(US11414431, Compound I-46 | US12221453, Compound I...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424885(US10508120, Compound I-1389 | US10577373, Compound...)
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM719104(US12221453, Compound I-48)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM424700(US10508120, Compound I-1204 | US10577373, Compound...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM565484(US11414431, Compound I-50 | US12221453, Compound I...)
Affinity DataKd:  5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
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