Compile Data Set for Download or QSAR
Report error Found 157 Enz. Inhib. hit(s) with all data for entry = 12610
TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713720(2-(6-((5,6-dichloro-1H- benzo[d]imidazol-1- yl)met...)
Affinity DataIC50: 22.4nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713720(2-(6-((5,6-dichloro-1H- benzo[d]imidazol-1- yl)met...)
Affinity DataIC50: 22.4nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713747(2-(difluoromethyl)-5-(6-((4- (2-fluorophenyl)-1H-1...)
Affinity DataIC50: 24nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713747(2-(difluoromethyl)-5-(6-((4- (2-fluorophenyl)-1H-1...)
Affinity DataIC50: 24nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713746(2-(6-((4-(3,5- dichlorophenyl)-1H-1,2,3- triazol-1...)
Affinity DataIC50: 25.7nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713722(2-(6-((5,6-dichloro-1H- benzo[d][1,2,3]triazol-1- ...)
Affinity DataIC50: 29.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713722(2-(6-((5,6-dichloro-1H- benzo[d][1,2,3]triazol-1- ...)
Affinity DataIC50: 29.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713723(2-(6-((5,6-dichloro-2H- benzo[d][1,2,3]triazol-2- ...)
Affinity DataIC50: 29.8nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713723(2-(6-((5,6-dichloro-2H- benzo[d][1,2,3]triazol-2- ...)
Affinity DataIC50: 29.8nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713765(2-(6-((5-bromo-2H- benzo[d][1,2,3]triazol-2- yl)me...)
Affinity DataIC50: 33.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713744(2-(6-((4-(3-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 33.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713753(2-(6-((5-chloro-4-(3- chlorophenyl)-1H-1,2,3- tria...)
Affinity DataIC50: 34.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713753(2-(6-((5-chloro-4-(3- chlorophenyl)-1H-1,2,3- tria...)
Affinity DataIC50: 34.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713743(2-(6-((4-(2-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 37.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713745(2-(6-((4-(3,4- dichlorophenyl)-1H-1,2,3- triazol-1...)
Affinity DataIC50: 37.9nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713764(2-(6-((6-bromo-1H- benzo[d][1,2,3]triazol-1- yl)me...)
Affinity DataIC50: 40.4nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713740(2-(difluoromethyl)-5-(6-((4- phenyl-1H-1,2,3-triaz...)
Affinity DataIC50: 40.9nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713759(2-(6-((5,6-dichloro-2-methyl- 1H-benzo[d]imidazol-...)
Affinity DataIC50: 42.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713742(2-(6-((4-(4-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 43.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713749(2-(6-((4-(3-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 43.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713724(2-(difluoromethyl)-5-(6-((4- phenyl-1H-imidazol-1-...)
Affinity DataIC50: 48.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713762(2-(6-((5-bromo-1H- benzo[d]imidazol-1- yl)methyl)p...)
Affinity DataIC50: 48.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713751(2-(6-((5-chloro-4-phenyl-1H- 1,2,3-triazol-1- yl)m...)
Affinity DataIC50: 48.4nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713763(2-(6-((5-bromo-1H- benzo[d][1,2,3]triazol-1- yl)me...)
Affinity DataIC50: 48.7nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713754(2-(6-(chloro(4-phenyl-1H- 1,2,3-triazol-1- yl)meth...)
Affinity DataIC50: 58.2nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713708(2-(4-((5,6-dichloro-1H- benzo[d]imidazol-1- yl)met...)
Affinity DataIC50: 60.2nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713761(2-(6-((6-bromo-1H- benzo[d]imidazol-1- yl)methyl)p...)
Affinity DataIC50: 61.8nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713755(2-(difluoromethyl)-5-(6-((4- (3,5-difluorophenyl)-...)
Affinity DataIC50: 66.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713748(2-(difluoromethyl)-5-(6-((4- (2,6-difluorophenyl)-...)
Affinity DataIC50: 66.7nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713732(2-(6-((5-chloro-4-(2- fluorophenyl)-1H-1,2,3- tria...)
Affinity DataIC50: 67.4nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713752(2-(6-((5-chloro-4-(2- chlorophenyl)-1H-1,2,3- tria...)
Affinity DataIC50: 81.5nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713758(2-(difluoromethyl)-5-(6-((5,6- dimethyl-1H- benzo[...)
Affinity DataIC50: 85.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM618071(US20230286970, Compound 234 | 2-(difluoromethyl)-5...)
Affinity DataIC50: 85.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM618071(US20230286970, Compound 234 | 2-(difluoromethyl)-5...)
Affinity DataIC50: 85.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713750(2-(4-((5-chloro-4-phenyl-1H- 1,2,3-triazol-1- yl)m...)
Affinity DataIC50: 87.9nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713727(2-(4-((4-(4-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 95.6nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713719(2-(6-((1H- benzo[d][1,2,3]triazol-1- yl)methyl)pyr...)
Affinity DataIC50: 103nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713736(2-(difluoromethyl)-5-(4-((4- (thiophen-2-yl)-1H-1,...)
Affinity DataIC50: 105nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713757(2-(6-((5,6-dichloro-2- (trifluoromethyl)-1H- benzo...)
Affinity DataIC50: 121nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713711(2-(4-((6-chloro-1H- benzo[d][1,2,3]triazol-1- yl)m...)
Affinity DataIC50: 129nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713735(2-(difluoromethyl)-5-(4-((4- (thiophen-3-yl)-1H-1,...)
Affinity DataIC50: 131nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713737(2-(difluoromethyl)-5-(4-(1- (4-phenyl-1H-1,2,3-tri...)
Affinity DataIC50: 149nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713756(2-(difluoromethyl)-5-(6-((4- (3,4,5-trifluoropheny...)
Affinity DataIC50: 149nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
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TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713709(2-(4-((1H- benzo[d][1,2,3]triazol-1- yl)methyl)phe...)
Affinity DataIC50: 171nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713709(2-(4-((1H- benzo[d][1,2,3]triazol-1- yl)methyl)phe...)
Affinity DataIC50: 171nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713760(2-(difluoromethyl)-5-(6-((5,6- dimethyl-1H- benzo[...)
Affinity DataIC50: 187nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713733(2-(difluoromethyl)-5-(4-((4- (pyridin-4-yl)-1H-1,2...)
Affinity DataIC50: 188nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713710(Mixture of three triazolic regioisomers | US122028...)
Affinity DataIC50: 190nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713712(1-(4-(5-(difluoromethyl)- 1,3,4-oxadiazol-2- yl)be...)
Affinity DataIC50: 190nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713721(2-(6-((3H-[1,2,3]triazolo[4,5- b]pyridin-3-yl)meth...)
Affinity DataIC50: 190nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

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