Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 12513
TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707322(2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)methyl)p...)
Affinity DataIC50: 8.30E+3nMAssay Description:Table 4: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707321((R)-2-((2-Amino-7-(6-(1-methylpiperidin-4-yl)pyrid...)
Affinity DataIC50: 1.60E+4nMAssay Description:Table 4: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707320((R)-2-((2-Amino-7-(6-(pyrrolidin-1-ylmethyl)pyridi...)
Affinity DataIC50: 2.70E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707321((R)-2-((2-Amino-7-(6-(1-methylpiperidin-4-yl)pyrid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707322(2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)methyl)p...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707323((R)-2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707324((R)-2-((2-Amino-7-(2-(1-methylpiperidin-4-yl)pyrim...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
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TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707320((R)-2-((2-Amino-7-(6-(pyrrolidin-1-ylmethyl)pyridi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707321((R)-2-((2-Amino-7-(6-(1-methylpiperidin-4-yl)pyrid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707322(2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)methyl)p...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707323((R)-2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707324((R)-2-((2-Amino-7-(2-(1-methylpiperidin-4-yl)pyrim...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707323((R)-2-((2-Amino-7-(6-((4-methylpiperazin-1-yl)meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 4: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707324((R)-2-((2-Amino-7-(2-(1-methylpiperidin-4-yl)pyrim...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 4: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent