Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 12508
TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707275BDBM707275(US12161642, Example 5i)
Affinity DataIC50: 33.6nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707277BDBM707277(US12161642, Example 5k)
Affinity DataIC50: 42.9nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707255BDBM707255(US12161642, Library ID D433-1582)
Affinity DataIC50: 61.4nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707272BDBM707272(US12161642, Example 5f)
Affinity DataIC50: 91.6nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707238BDBM707238(US12161642, Library ID D351-0310)
Affinity DataIC50: 98.1nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707263BDBM707263(US12161642, Example 4e)
Affinity DataIC50: 178nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707250BDBM707250(US12161642, Library ID D433-1848)
Affinity DataIC50: 227nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707269BDBM707269(US12161642, Example 5c)
Affinity DataIC50: 293nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707239BDBM707239(US12161642, Library ID D351-0414)
Affinity DataIC50: 346nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707271BDBM707271(US12161642, Example 5e)
Affinity DataIC50: 346nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707241BDBM707241(US12161642, Library ID D351-0319)
Affinity DataIC50: 491nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707268BDBM707268(US12161642, Example 5b)
Affinity DataIC50: 508nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707266BDBM707266(US12161642, Example 4h)
Affinity DataIC50: 511nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707279BDBM707279(US12161642, Example 5m)
Affinity DataIC50: 525nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707243BDBM707243(US12161642, Library ID D433-1748)
Affinity DataIC50: 570nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707242BDBM707242(US12161642, Library ID D433-1800)
Affinity DataIC50: 751nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707240BDBM707240(US12161642, Library ID D351-0303)
Affinity DataIC50: 808nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707245BDBM707245(US12161642, Library ID D433-1739)
Affinity DataIC50: 829nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707246BDBM707246(US12161642, Library ID D433-1798)
Affinity DataIC50: 1.02E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707249BDBM707249(US12161642, Library ID D433-1839)
Affinity DataIC50: 1.05E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707254BDBM707254(US12161642, Library ID D433-1585)
Affinity DataIC50: 1.25E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707237BDBM707237(US12161642, Library ID D351-0312)
Affinity DataIC50: 1.39E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707251BDBM707251(US12161642, Library ID D433-1831)
Affinity DataIC50: 1.57E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707244BDBM707244(US12161642, Library ID D433-1750)
Affinity DataIC50: 2.15E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707247BDBM707247(US12161642, Library ID D433-1741)
Affinity DataIC50: 2.86E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707253BDBM707253(US12161642, Library ID D433-1688)
Affinity DataIC50: 2.99E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707283BDBM707283(US12161642, Example 5q)
Affinity DataIC50: 3.62E+3nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707252BDBM707252(US12161642, Library ID D433-1841)
Affinity DataIC50: 3.75E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707248BDBM707248(US12161642, Library ID D433-1725)
Affinity DataIC50: 4.39E+3nMAssay Description:Table 1: A kinetic assay to monitor FECH enzymatic activity was adapted from a published protocol (Burden et a., Biochim Biophys Acta 1435, 191-197 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707282BDBM707282(US12161642, Example 5p)
Affinity DataIC50: 9.34E+3nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707276BDBM707276(US12161642, Example 5j)
Affinity DataIC50: 1.06E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707286BDBM707286(US12161642, Example 5t)
Affinity DataIC50: 1.68E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707284BDBM707284(US12161642, Example 5r)
Affinity DataIC50: 1.79E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707288BDBM707288(US12161642, Example 5v)
Affinity DataIC50: 1.87E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707289BDBM707289(US12161642, Example 5w)
Affinity DataIC50: 2.25E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707273BDBM707273(US12161642, Example 5g)
Affinity DataIC50: 2.73E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707285BDBM707285(US12161642, Example 5s)
Affinity DataIC50: 2.81E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707280BDBM707280(US12161642, Example 5n)
Affinity DataIC50: 3.41E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707287BDBM707287(US12161642, Example 5u)
Affinity DataIC50: 7.72E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707278BDBM707278(US12161642, Example 5l)
Affinity DataIC50: 7.80E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707267BDBM707267(US12161642, Example 5a)
Affinity DataIC50: 9.20E+4nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707281BDBM707281(US12161642, Example 5o)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707265BDBM707265(US12161642, Example 4g)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707264BDBM707264(US12161642, Example 4f)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707261BDBM707261(US12161642, Example 4c)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707262BDBM707262(US12161642, Example 4d)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707259BDBM707259(US12161642, Example 4a)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707260BDBM707260(US12161642, Example 4b)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707257BDBM707257(US12161642, Example 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetFerrochelatase, mitochondrial(Human)
Indiana University

US Patent
LigandChemical structure of BindingDB Monomer ID 707258BDBM707258(US12161642, Example 3)
Affinity DataIC50: 1.00E+5nMAssay Description:Table 2: Using the same screening methods as in the FECH activity assay, compounds 1, 2, 3, 4a˜4h, and 5a˜5w were tested for FECH inhibition (Table 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

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