Compile Data Set for Download or QSAR
Report error Found 214 Enz. Inhib. hit(s) with all data for entry = 12241
TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689477(US12053473, Example I-340)
Affinity DataIC50: 1nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689307(US12053473, Example I-45)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689366(US12053473, Example I-165)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689367(US12053473, Example I-166)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689395(US12053473, Example I-234)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689397(US12053473, Example I-236)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689401(US12053473, Example I-240)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689405(US12053473, Example I-244)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689407(US12053473, Example I-246)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689409(US12053473, Example I-248)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689415(US12053473, Example I-254)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689421(US12053473, Example I-260)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689422(US12053473, Example I-261)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689423(US12053473, Example I-262)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689434(US12053473, Example I-275)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689437(US12053473, Example I-278)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689441(US12053473, Example I-285)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689442(US12053473, Example I-286)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689443(US12053473, Example I-287)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689460(US12053473, Example I-314)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689487(US12053473, Example I-352)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689488(US12053473, Example I-353)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689490(US12053473, Example I-355)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689494(US12053473, Example I-359)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689270(US12053473, Example I-2 | US12053473, Example I-1)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689270(US12053473, Example I-2 | US12053473, Example I-1)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689278(US12053473, Example I-7)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689282(US12053473, Example I-9)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689322(US12053473, Example I-53)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689365(US12053473, Example I-164)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689385(US12053473, Example I-220)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689399(US12053473, Example I-238)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689413(US12053473, Example I-252)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689417(US12053473, Example I-256)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689419(US12053473, Example I-258)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689424(US12053473, Example I-263)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689435(US12053473, Example I-276)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689452(US12053473, Example I-298)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689454(US12053473, Example I-307)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689459(US12053473, Example I-313)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689461(US12053473, Example I-315)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689467(US12053473, Example I-321)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689468(US12053473, Example I-322)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689492(US12053473, Example I-357)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689306(US12053473, Example I-44)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689308(US12053473, Example I-46)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689323(US12053473, Example I-54)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689357(US12053473, Example I-107)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689389(US12053473, Example I-224)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

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