Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 12105
TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679377(US11999723, Compound 8s)
Affinity DataKi:  66nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM50458543(CHEMBL4208079 | US11999723, Compound 8x)
Affinity DataKi:  67nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679381(US11999723, Compound 8w)
Affinity DataKi:  75nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679395(US11999723, Compound 9v)
Affinity DataKi:  100nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679399(US11999723, Compound 9z)
Affinity DataKi:  110nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679376(US11999723, Compound 8r)
Affinity DataKi:  110nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679379(US11999723, Compound 8u)
Affinity DataKi:  130nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679375(US11999723, Compound 8q)
Affinity DataKi:  140nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679397(US11999723, Compound 9x)
Affinity DataKi:  150nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679373(US11999723, Compound 8o)
Affinity DataKi:  150nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679374(US11999723, Compound 8p)
Affinity DataKi:  170nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679400(US11999723, Compound 9aa)
Affinity DataKi:  230nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679380(US11999723, Compound 8v)
Affinity DataKi:  240nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679398(US11999723, Compound 9y)
Affinity DataKi:  260nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679401(US11999723, Compound 9bb)
Affinity DataKi:  330nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679378(US11999723, Compound 8t)
Affinity DataKi:  350nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679371(US11999723, Compound 8m)
Affinity DataKi:  480nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM50458542(CHEMBL4218738 | US11999723, Compound 8n)
Affinity DataKi:  510nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679392(US11999723, Compound 9s)
Affinity DataKi:  570nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679396(US11999723, Compound 9w)
Affinity DataKi:  710nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679370(US11999723, Compound 8l)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679389(US11999723, Compound 9p)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679390(US11999723, Compound 9q)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679363(US11999723, Compound 8e)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679394(US11999723, Compound 9u)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679393(US11999723, Compound 9t)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679368(US11999723, Compound 8j)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679383(US11999723, Compound 9h)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679384(US11999723, Compound 9i)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679369(US11999723, Compound 8k)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679386(US11999723, Compound 9m)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679388(US11999723, Compound 9o)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679361(US11999723, Compound 8c)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679164(US11999723, Compound 7b)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679175(US11999723, Compound 8b)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679365(US11999723, Compound 8g)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679364(US11999723, Compound 8f)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679149(US11999723, Compound 6c)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679367(US11999723, Compound 8i)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679366(US11999723, Compound 8h)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679171(US11999723, Compound 8a)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679362(US11999723, Compound 8d)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679382(US11999723, Compound 9g)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679387(US11999723, Compound 9n)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679385(US11999723, Compound 9l)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679153(US11999723, Compound 7a)
Affinity DataKi:  1.27E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679391(US11999723, Compound 9r)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679402(US11999723, Compound 9cc)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679144(US11999723, Compound 6b)
Affinity DataKi:  1.95E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetMacrophage migration inhibitory factor(Human)
Yale University

US Patent
LigandPNGBDBM679372(US11999723, Compound 9f)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

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