Compile Data Set for Download or QSAR
Report error Found 124 Enz. Inhib. hit(s) with all data for entry = 12026
TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582221BDBM50582221(CHEMBL5090028 | US11708359, Example 60 | US1197498...)
Affinity DataIC50: 0.00700nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609871BDBM609871(US11708359, Example 62 | (rac)-(2s,4s)-2-(6-(4-(te...)
Affinity DataIC50: 0.0190nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582222BDBM50582222(CHEMBL5074982 | US11708359, Example 71 | US1197498...)
Affinity DataIC50: 0.0240nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609880BDBM609880(US11708359, Example 69 | (rac)-(2s,4s)-2-(6-(4-(1-...)
Affinity DataIC50: 0.0340nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609878BDBM609878(US11708359, Example 67 | (rac)-(2s,4s)-2-(6-(3-Chl...)
Affinity DataIC50: 0.0750nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609885BDBM609885(US11708359, Example 74 | (rac)-(2s,4s)-2-(6-(4-Iso...)
Affinity DataIC50: 0.210nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609870BDBM609870(US11708359, Example 61 | (rac)-(2r,4s)-2-(6-(3-(te...)
Affinity DataIC50: 0.25nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609884BDBM609884(US11708359, Example 73 | (rac)-(2s,4s)-2-(6-(3-Iso...)
Affinity DataIC50: 0.25nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609886BDBM609886(US11708359, Example 75 | (rac)-(2s,4s)-2-(6-(4-Met...)
Affinity DataIC50: 0.340nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582218BDBM50582218(CHEMBL5090735 | US11708359, Example 32 | US1197498...)
Affinity DataIC50: 0.350nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609872BDBM609872(US11708359, Example 63 | (rac)-(2r,4s)-2-(6-(4-(te...)
Affinity DataIC50: 0.410nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609856BDBM609856(US11708359, Example 51 | (2s,4*S)-2-((l*R,6*S)-6-(...)
Affinity DataIC50: 0.520nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609881BDBM609881(US11708359, Example 70 | (rac)-(2r,4s)-2-(6-(4-(1-...)
Affinity DataIC50: 0.520nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609906BDBM609906((rac)-(2s,4*S)-2-((1*R,5*S,6*R)-6-(3-(tert-Butyl)p...)
Affinity DataIC50: 0.640nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609873BDBM609873(US11708359, Example 64 | (rac)-(2s,4s)-2-(6-(3-Cyc...)
Affinity DataIC50: 0.650nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582223BDBM50582223(CHEMBL5083796 | US11708359, Example 82 | US1197498...)
Affinity DataIC50: 0.690nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609876BDBM609876(US11708359, Example 66 | (rac)-(2s,4s)-2-(6-(4-Cyc...)
Affinity DataIC50: 0.690nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609891BDBM609891(US11708359, Example 78 | (2s,4S)-2-((1R,5S,6S)-6-(...)
Affinity DataIC50: 0.760nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609891BDBM609891(US11708359, Example 78 | (2s,4S)-2-((1R,5S,6S)-6-(...)
Affinity DataIC50: 0.930nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609891BDBM609891(US11708359, Example 78 | (2s,4S)-2-((1R,5S,6S)-6-(...)
Affinity DataIC50: 0.990nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609829BDBM609829(US11708359, Example 31 | (rac)-(2s,4s)-2-(1-(3-(1-...)
Affinity DataIC50: 1.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609853BDBM609853(US11708359, Example 48 | (2s,4*S)-2-((1*R,6*S)-6-(...)
Affinity DataIC50: 1.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609822BDBM609822(US11708359, Example 26 | (rac)-(2s,4s)-2-(1-(4-(1-...)
Affinity DataIC50: 1.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609866BDBM609866(US11708359, Example 58 | BDBM609867 | (rac)-(2s,4s...)
Affinity DataIC50: 1.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582215BDBM50582215(CHEMBL5082727 | US11708359, Example 5 | US11974987...)
Affinity DataIC50: 1.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609826BDBM609826(US11708359, Example 29 | (rac)-(2s,4s)-2-(1-(3-Phe...)
Affinity DataIC50: 1.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609915BDBM609915(US11708359, Example 101 | (2s,4S)-2-((1R,5S,6S)-6-...)
Affinity DataIC50: 1.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609854BDBM609854(US11708359, Example 49 | (rac)-(2s,4s)-2-(6-(3-(Tr...)
Affinity DataIC50: 1.60nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609924BDBM609924(US11708359, Example 109 | (2s,4S)-2-((1R,5S,6S)-6-...)
Affinity DataIC50: 1.60nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582226BDBM50582226(CHEMBL5092906 | US11708359, Example 118 | US119749...)
Affinity DataIC50: 1.60nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609825BDBM609825(US11708359, Example 28 | (rac)-(2s,4s)-2-(1-(4-Phe...)
Affinity DataIC50: 1.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609865BDBM609865(US11708359, Example 57 | (rac)-(2s,4s)-2-(6-(3-(Tr...)
Affinity DataIC50: 1.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609883BDBM609883(US11708359, Example 72 | (rac)-(2s,4s)-2-(6-(4-Cyc...)
Affinity DataIC50: 2.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609802BDBM609802(US11708359, Example 9 | (rac)-(2s,4s)-2-(1-(4-Isop...)
Affinity DataIC50: 2.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609804BDBM609804(US11708359, Example 11 | (2s,4*R)-2-((1*S,5*R)-1-(...)
Affinity DataIC50: 2.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609803BDBM609803(US11708359, Example 10 | (2s,4*S)-2-((1*R,5*S)-1-(...)
Affinity DataIC50: 2.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609831BDBM609831(US11708359, Example 33 | (rac)-(2s,4s)-2-(1-(2-Met...)
Affinity DataIC50: 2.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609860BDBM609860(US11708359, Example 54 | (rac)-(2s,4s)-2-(6-(4-(Tr...)
Affinity DataIC50: 2.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609887BDBM609887(US11708359, Example 76 | (rac)-(2r,4s)-2-(6-(4-Met...)
Affinity DataIC50: 2.60nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 670993BDBM670993((2s,4*R)-2-((1*S,6*R)-6-(m-Tolyl)-3-azabicyclo[4.1...)
Affinity DataIC50: 2.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609903BDBM609903(US11708359, Example 90 | (2s,4S)-2-((1R,5S,6S)-6-(...)
Affinity DataIC50: 2.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609827BDBM609827(US11708359, Example 30 | (rac)-(2s,4s)-2-(1-(3-Chl...)
Affinity DataIC50: 2.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609896BDBM609896(US11708359, Example 83 | (2r,4S)-2-((1R,5S,6S)-6-(...)
Affinity DataIC50: 2.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609832BDBM609832(US11708359, Example 34 | (rac)-(2s,4s)-2-(1-(2-Met...)
Affinity DataIC50: 3.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609835BDBM609835(US11708359, Example 36 | (rac)-(2s,4s)-2-(1-(3-Met...)
Affinity DataIC50: 3.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609907BDBM609907(US11708359, Example 94 | (rac)-(2s,4s)-2-(1-(4-Eth...)
Affinity DataIC50: 3.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609821BDBM609821(US11708359, Example 25 | (rac)-(2s,4s)-2-(1-(4-Met...)
Affinity DataIC50: 3.60nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609851BDBM609851(US11708359, Example 46 | (rac)-(2s,4s)-2-(6-(3-Flu...)
Affinity DataIC50: 3.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50582217BDBM50582217(CHEMBL5079900 | US11708359, Example 17 | US1197498...)
Affinity DataIC50: 3.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 609874BDBM609874(US11708359, Example 65 | (rac)-(2r,4s)-2-(6-(3-Cyc...)
Affinity DataIC50: 4nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

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