Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 11834
TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50: 3.20E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50: 3.30E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM47032(cid_3883 | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)p...)
Affinity DataIC50: 3.30E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM47032(cid_3883 | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)p...)
Affinity DataIC50: 3.50E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50: 7.40E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50: 8.70E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651962(US11903935, Compound IA-3)
Affinity DataIC50: 2.14E+4nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651962(US11903935, Compound IA-3)
Affinity DataIC50: 2.83E+4nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent