Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 10639
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651470(US11897898, Example 3)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651498(US11897898, Example 47)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651497(US11897898, Example 46)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651496(US11897898, Example 45)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651495(US11897898, Example 44)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651494(US11897898, Example 41)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651493(US11897898, Example 40)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651469(US11897898, Example 22 | (S)-55-Bromo-10-methyl-14...)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651491(US11897898, Example 38)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651490(US11897898, Example 33)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651489(US11897898, Example 32)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651488(US11897898, Example 31)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651487(US11897898, Example 30)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651486(US11897898, Example 28)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651485(US11897898, Example 25)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651469(US11897898, Example 22 | (S)-55-Bromo-10-methyl-14...)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651469(US11897898, Example 22 | (S)-55-Bromo-10-methyl-14...)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651471(US11897898, Example 4)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651472(US11897898, Example 7)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651473(US11897898, Example 8)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651474(US11897898, Example 9)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651475(US11897898, Example 11)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651476(US11897898, Example 12)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651477(US11897898, Example 13)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651478(US11897898, Example 14)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651479(US11897898, Example 15)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651480(US11897898, Example 17)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651481(US11897898, Example 20)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651482(US11897898, Example 21)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651484(US11897898, Example 23)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651499(US11897898, Example 6)
Affinity DataIC50: 550nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651500(US11897898, Example 18)
Affinity DataIC50: 550nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651501(US11897898, Example 2 | (R)-55-Bromo-10-methyl-14H...)
Affinity DataIC50: 5.50E+3nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651502(US11897898, Example 5)
Affinity DataIC50: 5.50E+3nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651503(US11897898, Example 24)
Affinity DataIC50: 5.50E+3nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651504(US11897898, Example 37)
Affinity DataIC50: 5.50E+3nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651505(US11897898, Example 42)
Affinity DataIC50: 1.00E+4nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent