Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 11575
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628211(US11795169, Example 7)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628212(US11795169, Example 8)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628205(US11795169, Example 2)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628235(US11795169, Example 29)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628231(US11795169, Example 25)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628232(US11795169, Example 26)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628233(US11795169, Example 27)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628234(US11795169, Example 28)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628243(US11795169, Example 37)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628244(US11795169, Example 38)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628245(US11795169, Example 39)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628246(US11795169, Example 40)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628239(US11795169, Example 33)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628241(US11795169, Example 35)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628242(US11795169, Example 36)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628217(US11795169, Example 13)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628218(US11795169, Example 14)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628219(US11795169, Example 15)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628221(US11795169, Example 16)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628213(US11795169, Example 9)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628214(US11795169, Example 10)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628215(US11795169, Example 11)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628229(US11795169, Example 23)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628222(US11795169, Example 17)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628224(US11795169, Example 18)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628225(US11795169, Example 19)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628267(US11795169, Example 64)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628268(US11795169, Example 65)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628263(US11795169, Example 58)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628264(US11795169, Example 61)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628265(US11795169, Example 62)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628277(US11795169, Example 76)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628278(US11795169, Example 77)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628271(US11795169, Example 68)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628272(US11795169, Example 69)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628273(US11795169, Example 70)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628251(US11795169, Example 45)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628252(US11795169, Example 46)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628254(US11795169, Example 48)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628247(US11795169, Example 41)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628248(US11795169, Example 42)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628249(US11795169, Example 43)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628259(US11795169, Example 53)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628260(US11795169, Example 55)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628261(US11795169, Example 56)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628262(US11795169, Example 57)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628255(US11795169, Example 49)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628256(US11795169, Example 50)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628257(US11795169, Example 51)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628258(US11795169, Example 52)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

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