Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 11469
TargetRho-associated protein kinase 2(Human)
City of Hope

US Patent
LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 1.5nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetGlycogen synthase kinase-3(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetGlycogen synthase kinase-3(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
City of Hope

US Patent
LigandPNGBDBM7497(14-bromo-3,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^{...)
Affinity DataIC50: 18nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
City of Hope

US Patent
LigandPNGBDBM618530(US11759530, Compound Table1.9)
Affinity DataIC50: 30nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetTGF-beta receptor type-1(Human)
City of Hope

US Patent
LigandPNGBDBM50298220(2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50: 47nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetSerine/threonine-protein kinase receptor R3(Human)
City of Hope

US Patent
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50: 51nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetActivin receptor type-1B(Human)
City of Hope

US Patent
LigandPNGBDBM50298220(2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50: 129nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
City of Hope

US Patent
LigandPNGBDBM420289(HL-7 | US11759530, Compound Table1.6)
Affinity DataIC50: 130nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCasein kinase I homolog hhp1(Fission yeast)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 200nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50: 250nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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PDB3D3D Structure (crystal)
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 320nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetSerine/threonine-protein kinase pim-1(Human)
City of Hope

US Patent
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 340nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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PDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 500nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 11(Human)
City of Hope

US Patent
LigandPNGBDBM420289(HL-7 | US11759530, Compound Table1.6)
Affinity DataIC50: 550nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
City of Hope

US Patent
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50: 740nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetPIM2(Human)
City of Hope

US Patent
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 3.45E+3nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
City of Hope

US Patent
LigandPNGBDBM618481(US11759530, Compound Table1.4)
Affinity DataIC50: 1.02E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetInositol-trisphosphate 3-kinase A(Human)
City of Hope

US Patent
LigandPNGBDBM618482(US11759530, Compound Table1.5)
Affinity DataIC50: 1.02E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
City of Hope

US Patent
LigandPNGBDBM50298220(2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50: 1.06E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCasein kinase I isoform delta(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 3.00E+5nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50: 1.20E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50: 4.50E+6nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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TargetPI3a/d(Human)
City of Hope

US Patent
LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50: 2.00E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
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