Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 11365
TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609905(US11708366, Example 9)
Affinity DataIC50: 2.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609965(US11708366, Example 35b)
Affinity DataIC50: 3.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609946(US11708366, Example 21)
Affinity DataIC50: 4.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609846(US11708366, Example 5)
Affinity DataIC50: 5.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609966(US11708366, Example 36)
Affinity DataIC50: 6.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609075(US11708366, Example 1)
Affinity DataIC50: 6.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609830(US11708366, Example 4)
Affinity DataIC50: 7.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609961(US11708366, Example 32)
Affinity DataIC50: 7.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609895(US11708366, Example 8)
Affinity DataIC50: 7.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609977(US11708366, Example 84)
Affinity DataIC50: 8.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609811(US11708366, Example 3)
Affinity DataIC50: 8.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609970(US11708366, Example 38)
Affinity DataIC50: 8.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609976(US11708366, Example 83)
Affinity DataIC50: 9.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609948(US11708366, Example 22)
Affinity DataIC50: 1.10E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609968(US11708366, Example 37)
Affinity DataIC50: 1.20E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
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Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609938(US11708366, Example 20)
Affinity DataIC50: 1.20E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609973(US11708366, Example 82)
Affinity DataIC50: 1.20E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609964(9-(2-(5-azaspiro[2.3]hexan-5-yl)pyrimidin-4-yl)-1-...)
Affinity DataIC50: 1.20E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609971(US11708366, Example 44)
Affinity DataIC50: 1.30E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609972(US11708366, Example 81)
Affinity DataIC50: 1.30E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609959(US11708366, Example 30)
Affinity DataIC50: 1.30E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609960(US11708366, Example 31)
Affinity DataIC50: 1.50E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609954(US11708366, Example 26)
Affinity DataIC50: 1.60E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609962(US11708366, Example 33)
Affinity DataIC50: 2.40E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609955(US11708366, Example 27)
Affinity DataIC50: 2.50E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609951(US11708366, Example 24)
Affinity DataIC50: 3.30E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609798(US11708366, Example 2)
Affinity DataIC50: 3.60E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609868(US11708366, Example 6b)
Affinity DataIC50: 4.40E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609958(US11708366, Example 29)
Affinity DataIC50: 5.70E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609950(US11708366, Example 23)
Affinity DataIC50: 6.10E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609953(US11708366, Example 25)
Affinity DataIC50: 6.20E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609882(US11708366, Example 7)
Affinity DataIC50: 7.60E+4nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609956(US11708366, Example 28)
Affinity DataIC50: 1.10E+5nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609858(1-(4-chloro-3-fluorophenyl)-9-(5-((1R,2R)-2-(trifl...)
Affinity DataIC50: 1.90E+5nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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