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Compile Data Set for Download or QSAR
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Found
9
Enz. Inhib. hit(s) with all data for entry = 11345
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM520651
(US11147816, PD318088 | US11701360, PD318088)
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Affinity Data
IC50: 1.40nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
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PDB
3D Structure (crystal)
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Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM50531540
(CHEBI:75998 | GSK-1120212 | GSK1120212 | JTP 74057...)
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Affinity Data
IC50: 2.16nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM520648
(US11147816, AZD8330 | US11701360, AZD8330)
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Affinity Data
IC50: 7nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM520649
(US11147816, Binimetinib (ARRY-162, ARRY-438162) | ...)
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Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM104963
(CHEMBL507361 | US8575391, Q | US11147816, PD032590...)
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Affinity Data
IC50: 13.7nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Human)
Genuv
US Patent
Ligand
BDBM520650
(US11147816, Refametinib (RDEA119, Bay | US11701360...)
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Affinity Data
IC50: 19nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 2
(Human)
Genuv
US Patent
Ligand
BDBM520650
(US11147816, Refametinib (RDEA119, Bay | US11701360...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM50010462
(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
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Affinity Data
IC50: 160nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM50014412
(Pimasertib | US11147816, Pimasertib (AS703026) | U...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
Copy Rxn URL