Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 11291
TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: 0.372nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: 0.372nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: 0.640nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)
Affinity DataIC50: 1nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: 1nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605424(US11672785, Compound C | US20250114338, Example 15...)
Affinity DataIC50: 1.35nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)
Affinity DataIC50: 1.62nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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PDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605419(US11672785, Example Fulvestrant)
Affinity DataIC50: 2.29nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605421(US11672785, Compound B | US20240131013, Compound B)
Affinity DataIC50: 2.69nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
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TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50542087(CHEMBL4635493 | US11672785, Goodacre Compound 107 ...)
Affinity DataIC50: 2.82nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent