Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 11276
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599210(CHEMBL5170316)
Affinity DataIC50: 10nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599211(CHEMBL5196336)
Affinity DataIC50: 10nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599212(CHEMBL5176405)
Affinity DataIC50: 10nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599213(CHEMBL5187441)
Affinity DataIC50: 11nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599215(CHEMBL5171677)
Affinity DataIC50: 12nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50599214(CHEMBL5209855)
Affinity DataIC50: 13nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604834(US11661427, Example 15)
Affinity DataIC50: 18nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604826(US11661427, Example 7)
Affinity DataIC50: 20nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604827(US11661427, Example 8)
Affinity DataIC50: 21nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604829(US11661427, Example 10)
Affinity DataIC50: 23nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604828(US11661427, Example 9)
Affinity DataIC50: 23nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604820(US11661427, Example 1 | 3-({2-[(2R)-2-hydroxy-2-(4...)
Affinity DataIC50: 24nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604830(US11661427, Example 11)
Affinity DataIC50: 26nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604831(US11661427, Example 12)
Affinity DataIC50: 29nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604832(US11661427, Example 13)
Affinity DataIC50: 49nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50157702(CHEMBL3786639 | US11136336, Med. Chem. 2016, 59, 2...)
Affinity DataIC50: 52nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604835(WO2017/060488, Example 28 | 5- ({2-[2-(4-Chlorophe...)
Affinity DataIC50: 366nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM604836(WO2017/060488, Example 29 | 6-({2-[2-(4-Chlorophen...)
Affinity DataIC50: 1.12E+3nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2023
Entry Details
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