Compile Data Set for Download or QSAR
Report error Found 247 Enz. Inhib. hit(s) with all data for entry = 11254
TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 0.169nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249469(US9434727, 68 | US10072016, Compound 68 | US977701...)
Affinity DataIC50: 1.37nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249485(US9434727, 83 | US10072016, Compound 83 | US977701...)
Affinity DataIC50: 1.37nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 1.37nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 1.62nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 2.88nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249554(US9434727, 152 | US10072016, Compound 152 | US9777...)
Affinity DataIC50: 3.10nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249522(US9434727, 120 | US10072016, Compound 120 | US9777...)
Affinity DataIC50: 3.45nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 4.13nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249481(US9434727, 79 | US10072016, Compound 79 | US977701...)
Affinity DataIC50: 4.35nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249464(US9434727, 63 | US10072016, Compound 63 | US977701...)
Affinity DataIC50: 4.46nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249564(US9434727, 162 | US10072016, Compound 162 | US9777...)
Affinity DataIC50: 4.82nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249552(US9434727, 150 | US10072016, Compound 150 | US9777...)
Affinity DataIC50: 4.84nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249485(US9434727, 83 | US10072016, Compound 83 | US977701...)
Affinity DataIC50: 4.85nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249544(US9434727, 142 | US10072016, Compound 142 | US9777...)
Affinity DataIC50: 4.88nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 5.12nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249543(US9434727, 141 | US10072016, Compound 141 | US9777...)
Affinity DataIC50: 5.24nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249465(US9434727, 64 | US10072016, Compound 64 | US977701...)
Affinity DataIC50: 5.36nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249519(US9434727, 117 | US10072016, Compound 117 | US9777...)
Affinity DataIC50: 5.48nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249563(US9434727, 161 | US10072016, Compound 161 | US9777...)
Affinity DataIC50: 5.74nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249559(US9434727, 157 | US10072016, Compound 157 | US9777...)
Affinity DataIC50: 5.84nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249551(US9434727, 149 | US10072016, Compound 149 | US9777...)
Affinity DataIC50: 5.91nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 6.04nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249481(US9434727, 79 | US10072016, Compound 79 | US977701...)
Affinity DataIC50: 6.10nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249546(US9434727, 144 | US10072016, Compound 144 | US9777...)
Affinity DataIC50: 6.17nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249533(US9434727, 131 | US10072016, Compound 131 | US9777...)
Affinity DataIC50: 6.36nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249534(US9434727, 132 | US10072016, Compound 132 | US9777...)
Affinity DataIC50: 6.75nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249513(US9434727, 111 | US10072016, Compound 111 | US9777...)
Affinity DataIC50: 6.89nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249476(US9434727, 75 | US10072016, Compound 75 | US977701...)
Affinity DataIC50: 6.95nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249496(US9434727, 94 | US10072016, Compound 94 | US977701...)
Affinity DataIC50: 6.96nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249493(US9434727, 91 | US10072016, Compound 91 | US977701...)
Affinity DataIC50: 7.06nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249477(US9434727, 76 | US10072016, Compound 76 | US977701...)
Affinity DataIC50: 7.40nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 7.41nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249503(US9434727, 101 | US10072016, Compound 101 | US9777...)
Affinity DataIC50: 7.44nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249467(US9434727, 66 | US10072016, Compound 66 | US977701...)
Affinity DataIC50: 7.5nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249547(US9434727, 145 | US10072016, Compound 145 | US9777...)
Affinity DataIC50: 7.57nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249497(US9434727, 95 | US10072016, Compound 95 | US977701...)
Affinity DataIC50: 7.78nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249489(US9434727, 87 | US10072016, Compound 87 | US977701...)
Affinity DataIC50: 7.80nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 7.96nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249495(US9434727, 93 | US10072016, Compound 93 | US977701...)
Affinity DataIC50: 8nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249561(US9434727, 159 | US10072016, Compound 159 | US9777...)
Affinity DataIC50: 8.06nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249468(US9434727, 67 | US10072016, Compound 67 | US977701...)
Affinity DataIC50: 8.31nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 8.5nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandPNGBDBM249515(US9434727, 113 | US10072016, Compound 113 | US9777...)
Affinity DataIC50: 8.57nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

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