Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 11237
TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601762(US11643395, Compound 8)
Affinity DataIC50: 26.2nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601756(US11643395, Compound 1)
Affinity DataIC50: 100nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601758(US11643395, Compound 3)
Affinity DataIC50: 400nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601757(US11643395, Compound 2)
Affinity DataIC50: 500nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601760(US11643395, Compound 6)
Affinity DataIC50: 700nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601759(US11643395, Compound 5)
Affinity DataIC50: 2.43E+3nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 4.08E+4nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601761(US11643395, Compound 7)
Affinity DataIC50: 5.87E+4nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM85515(CAS_83-07-8 | NSC_2151 | Ampyrone | US11643395, Co...)
Affinity DataIC50: 6.97E+4nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601760(US11643395, Compound 6)
Affinity DataKi:  2.40E+3nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
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TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM601759(US11643395, Compound 5)
Affinity DataKi:  5.67E+3nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent

TargetCholinesterase(Human)
Individual

US Patent
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataKi:  2.15E+4nMAssay Description:In-vitro butyryl cholinesterase inhibitory activity was performed in 96-well microplates, 0.5 mM test compound in methanol, was incubated with 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent