Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 11232
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601690(US11639355, Example 11-I)
Affinity DataIC50: 0.240nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601694(US11639355, Example 14-II)
Affinity DataIC50: 0.25nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601684(US11639355, Example 7-II)
Affinity DataIC50: 0.440nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601687(US11639355, Example 10-I)
Affinity DataIC50: 0.590nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601692(US11639355, Example 12-I)
Affinity DataIC50: 0.690nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601679(US11639355, Example 1-I)
Affinity DataIC50: 0.710nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601685(US11639355, Example 8-I)
Affinity DataIC50: 0.790nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601686(US11639355, Example 9I)
Affinity DataIC50: 0.870nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601695(US11639355, Example 15)
Affinity DataIC50: 1.10nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
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Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601683(US11639355, Example 5)
Affinity DataIC50: 1.12nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
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Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601680(US11639355, Example 2)
Affinity DataIC50: 1.64nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
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Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601693(US11639355, Example 13-I)
Affinity DataIC50: 2.86nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601681(US11639355, Example 3)
Affinity DataIC50: 3.07nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601682(US11639355, Example 4)
Affinity DataIC50: 4.57nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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