Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 11228
TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443430(US10654866, Example 1B | US11117902, Example 1A | ...)
Affinity DataKi:  0.310nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443444(US10654866, Example 4B | US11117902, Example 4A | ...)
Affinity DataKi:  0.340nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443449(US10654866, Example 3B | US11117902, Example 3A | ...)
Affinity DataKi:  0.590nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443450(US10654866, Example 4 | US11117902, Example 4 | US...)
Affinity DataKi:  0.640nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443433(US10654866, Example 2A | US11117902, Example 2B | ...)
Affinity DataKi:  0.650nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443428(US10654866, Example 1 | Racemic 5-(4-{2-[3-(Fluoro...)
Affinity DataKi:  0.870nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443442(US10654866, Example 8A | US11117902, Example 8A | ...)
Affinity DataKi:  0.940nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443448(US10654866, Example 6B | US11117902, Example 6A | ...)
Affinity DataKi:  1.13nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443446(US10654866, Example 5B | US11117902, Example 5A | ...)
Affinity DataKi:  1.30nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443440(US10654866, Example 7 | US11634426, Example 7)
Affinity DataKi:  1.55nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443432(US10654866, Example 2 | Racemic 5-(4-{2- [3-(fluor...)
Affinity DataKi:  2.17nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443444(US10654866, Example 4B | US11117902, Example 4A | ...)
Affinity DataKi:  2.34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3A | US10654866, Example 3 | U...)
Affinity DataKi:  2.36nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443430(US10654866, Example 1B | US11117902, Example 1A | ...)
Affinity DataKi:  2.79nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443449(US10654866, Example 3B | US11117902, Example 3A | ...)
Affinity DataKi:  2.79nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443438(US10654866, Example 5 | US11117902, Example 5 | US...)
Affinity DataKi:  2.82nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443441(US10654866, Example 8 | US11117902, Example 8 | US...)
Affinity DataKi:  3.20nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443439(US10654866, Example 6 | US11117902, Example 6 | US...)
Affinity DataKi:  4.14nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443442(US10654866, Example 8A | US11117902, Example 8A | ...)
Affinity DataKi:  5.44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443448(US10654866, Example 6B | US11117902, Example 6A | ...)
Affinity DataKi:  5.71nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443428(US10654866, Example 1 | Racemic 5-(4-{2-[3-(Fluoro...)
Affinity DataKi:  5.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443446(US10654866, Example 5B | US11117902, Example 5A | ...)
Affinity DataKi:  6.56nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3A | US10654866, Example 3 | U...)
Affinity DataKi:  6.69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443432(US10654866, Example 2 | Racemic 5-(4-{2- [3-(fluor...)
Affinity DataKi:  6.78nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443433(US10654866, Example 2A | US11117902, Example 2B | ...)
Affinity DataKi:  7.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM518821(US11117902, Example 3B | US11634426, Example 3A)
Affinity DataKi:  8.11nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443447(US10654866, Example 6A | US11117902, Example 6B | ...)
Affinity DataKi:  8.53nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443440(US10654866, Example 7 | US11634426, Example 7)
Affinity DataKi:  8.55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443443(US10654866, Example 8B | US11117902, Example 8B | ...)
Affinity DataKi:  9.33nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443441(US10654866, Example 8 | US11117902, Example 8 | US...)
Affinity DataKi:  11.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443450(US10654866, Example 4 | US11117902, Example 4 | US...)
Affinity DataKi:  12.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443429(US10654866, Example 1A | US11117902, Example 1B | ...)
Affinity DataKi:  12.4nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443445(US10654866, Example 5A | US11117902, Example 5B | ...)
Affinity DataKi:  12.5nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443439(US10654866, Example 6 | US11117902, Example 6 | US...)
Affinity DataKi:  15.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443437(US10654866, Example 4A | US11117902, Example 4B | ...)
Affinity DataKi:  16.8nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443438(US10654866, Example 5 | US11117902, Example 5 | US...)
Affinity DataKi:  19.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM518821(US11117902, Example 3B | US11634426, Example 3A)
Affinity DataKi:  27.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443447(US10654866, Example 6A | US11117902, Example 6B | ...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443437(US10654866, Example 4A | US11117902, Example 4B | ...)
Affinity DataKi:  55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443429(US10654866, Example 1A | US11117902, Example 1B | ...)
Affinity DataKi:  57.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM443434(US10654866, Example 2B | US11117902, Example 2A | ...)
Affinity DataKi:  60.4nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443443(US10654866, Example 8B | US11117902, Example 8B | ...)
Affinity DataKi:  66.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443445(US10654866, Example 5A | US11117902, Example 5B | ...)
Affinity DataKi:  81.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
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TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443434(US10654866, Example 2B | US11117902, Example 2A | ...)
Affinity DataKi:  294nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent