Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 11145
TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594684(N-(6-(6,8-Dioxo-2,7-diazaspiro[4.5]decane-2-carbon...)
Affinity DataKd:  94nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594694(8-(Benzo[d]thiazol-2-yl)-1,3,8-triazaspiro[4.5]dec...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594693(8-Benzoyl-1,3,8-triazaspiro[4.5]decane-2,4-dione |...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594692((R)-8-(1,2,3,4-Tetrahydronaphthalene-1-carbonyl)-1...)
Affinity DataKd:  5nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594691((S)-8-(1,2,3,4-Tetrahydronaphthalene-1-carbonyl)-1...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594690(8-(2-((R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-th...)
Affinity DataKd:  106nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594658(US11584748, Example 25 | US11584748, Example 56 | ...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594688(2-(2-Aminobenzo[d]thiazole-6-carbonyl)-2,7-diazasp...)
Affinity DataKd:  26nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594687(tert-Butyl (6-(6,8-dioxo-2,7-diazaspiro[4.5]decane...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594686(tert-Butyl (5-(6,8-dioxo-2,7-diazaspiro[4.5]decane...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594685(2-(1-Acetylindoline-5-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  41nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594695(8-(Thiazolo[4,5-b]pyridin-2-yl)-1,3,8-triazaspiro[...)
Affinity DataKd:  17nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594683(N-(5-(6,8-Dioxo-2,7-diazaspiro[4.5]decane-2-carbon...)
Affinity DataKd:  45nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594682((+2-((S)-1,2,3,4-Tetrahydronaphthalene-1-carbonyl)...)
Affinity DataKd:  14nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594681((+)-2-((R)-1,2,3,4-Tetrahydronaphthalene-1-carbony...)
Affinity DataKd:  28nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594680(2-(Indoline-5-carbonyl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594679(2-(Benzo[d]oxazole-6-carbonyl)-2,7-diazaspiro[4.5]...)
Affinity DataKd:  10nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594678(2-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazasp...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594677(2-(Benzofuran-3-carbonyl)-2,7-diazaspiro[4.5]decan...)
Affinity DataKd:  9nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594676(N-(6-(6,8-Dioxo-2,7-diazaspiro[4.5]decan-2-yl)pyri...)
Affinity DataKd:  12nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594675(2-(1-Acetylindoline-6-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  8nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594705(8-(4-Nitrophenyl)-1,3,8-triazaspiro[4.5]decane-2,4...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594714(8-(Benzo[d]thiazole-5-carbonyl)-1,3,8-triazaspiro[...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594713(8-(Benzofuran-3-carbonyl)-2,8-diazaspiro[4.5]decan...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594712(8-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-2,8-diazasp...)
Affinity DataKd:  28nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594711((R)-8-(1,2,3,4-Tetrahydronaphthalene-1-carbonyl)-2...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594710((S)-8-(1,2,3,4- tetrahydronaphthalene- 1-carbonyl)...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594709(8-(Benzo[d]thiazole-5-carbonyl)-2,8-diazaspiro[4.5...)
Affinity DataKd:  15nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594708(8-Benzoyl-2,8-diazaspiro[4.5]decane-1,3-dione | US...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594707(Methyl 6-(1,3-dioxo-2,8-diazaspiro[4.5]decan-8-yl)...)
Affinity DataKd:  11nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594706(8-(4-Nitrophenyl)-2,8-diazaspiro[4.5]decane-1,3-di...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594674(2-(Indoline-6-carbonyl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  75nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594704(8-(Benzo[d]thiazol-2-yl)-2,8-diazaspiro[4.5]decane...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594703(8-(5-Nitropyridin-2-yl)-2,8-diazaspiro[4.5]decane-...)
Affinity DataKd:  23nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594702(8-(5-Nitropyridin-2-yl)-1,3,8-triazaspiro[4.5]deca...)
Affinity DataKd:  7nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594701(8-(Thiazolo[4,5-b]pyridin-2-yl)-2,8-diazaspiro[4.5...)
Affinity DataKd:  16nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594700(8-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-1,3,8-triaz...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594699(8-(Benzofuran-3-carbonyl)-1,3,8-triazaspiro[4.5]de...)
Affinity DataKd:  1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594698(N-(3-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decane-8-car...)
Affinity DataKd:  21nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594697(N-(4-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decane-8-car...)
Affinity DataKd:  27nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594696(Methyl 6-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-...)
Affinity DataKd:  34nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594644((+2-(4-Nitrophenyl)-2,7-diazaspiro[4.5]decane-6,8-...)
Affinity DataKd:  5nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594653(2-(Thiazolo[4,5-c]pyridin-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594652(2-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2,7-diazaspi...)
Affinity DataKd:  30nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594651(2-(Benzo[d]oxazol-2-yl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  46nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594650(2-(Oxazolo[4,5-b]pyridin-2-yl)-2,7-diazaspiro[4.5]...)
Affinity DataKd:  26nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594649(2-(6-Aminobenzo[d]thiazol-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  10nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594648(2-(Quinolin-2-yl)-2,7-diazaspiro[4.5]decane-6,8-di...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594647(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  15nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594646(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  96nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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