Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 11120
LigandPNGBDBM592313(2-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-(5-{[(2-hyd...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592311(2-[({2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-met...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592321((2S)-1-{[6-(cyanomethoxy)-2-(2-methylbiphenyl-3-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592325(2-({[2-(2-methylbiphenyl-3-yl)-6-(pyridin-2-ylmeth...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592323((2S)-1-{[6-(3-cyanopropoxy)-2-(2-methylbiphenyl-3-...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592322({[5-{[(2-hydroxyethyl)amino]methyl}-2-(2-methylbip...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592327(2-({[2-(2-methylbiphenyl-3-yl)-6-(2-morpholin-4-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592326(2-({[6-methoxy-2-(2-methylbiphenyl-3-yl)-1,3-benzo...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592331((2S)-1-({6-(cyanomethoxy)-2-[3-(2,3-dihydro-1,4-be...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM50540069(CHEMBL4637826 | US11572366, Example 8)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592334([(2-(2'-fluoro-2-methylbiphenyl-3-yl)-5-{[(2-hydro...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592309(3-(5-{[(2-hydroxyethyl)amino]methyl}-7-methyl-1,3-...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592307(2-({[7-methyl-2-(2-methylbiphenyl-3-yl)-1,3-benzox...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592306((2S)-1-{[7-methyl-2-(2-methylbiphenyl-3-yl)-1,3-be...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592312((2S)-1-({2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592310((2S)-1-({2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592317((2S)-1-{[4-methyl-2-(2-methylbiphenyl-3-yl)-1,3-be...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592316(2-({[2-(2-methylbiphenyl-3-yl)furo[3,2-b]pyridin-5...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592319(2-({[6-(2-methylbiphenyl-3-yl)furo[2,3-b]pyrazin-2...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592318(2-({[4-methyl-2-(2-methylbiphenyl-3-yl)-1,3-benzot...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592324(3-({[5-{[(2-hydroxyethyl)amino]methyl}-2-(2-methyl...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592329(4-{[5-{[(2-hydroxyethyl)amino]methyl}-7-methyl-2-(...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592296(2-({[2-(2-methylbiphenyl-3-yl)furo[2,3-b]pyridin-6...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592328(2-({[2-(2-methylbiphenyl-3-yl)[1,3]oxazolo[5,4-c]p...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592301((2S)-1-{[7-methyl-2-(2-methylbiphenyl-3-yl)furo[2,...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592333((2S)-1-{[2-(2-methylbiphenyl-3-yl)-1,3-benzoxazol-...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592300(2-({[7-methyl-2-(2-methylbiphenyl-3-yl)furo[2,3-c]...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592332((2S)-1-{[2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592299((2S)-1-{[7-methyl-2-(2-methylbiphenyl-3-yl)furo[3,...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592298(2-({[7-methyl-2-(2-methylbiphenyl-3-yl)furo[3,2-b]...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592330((2S)-1-({6-(cyanomethoxy)-2-[4-(2,3-dihydro-1,4-be...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592305(2-({[2-(2-methylbiphenyl-3-yl)furo[2,3-b]pyridin-5...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592335([(2-(3-cyclohex-1-en-1-yl-2-methylphenyl)-5-{[(2-h...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592302((2S)-1-{[2-(2-methylbiphenyl-3-yl)-1,3-benzoxazol-...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592308((2S)-1-{[2-(2-cyanobiphenyl-3-yl)-7-methyl-1,3-ben...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592297((2S)-1-{[2-(2-methylbiphenyl-3-yl)furo[2,3-b]pyrid...)
Affinity DataIC50: 550nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592315((2S)-1-{[2-(2-methylbiphenyl-3-yl)furo[3,2-b]pyrid...)
Affinity DataIC50: 550nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592314((2S)-1-{[2-(2-methylbiphenyl-3-yl)-1,3-benzothiazo...)
Affinity DataIC50: 550nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592320((2S)-1-{[6-(2-methylbiphenyl-3-yl)furo[2,3-b]pyraz...)
Affinity DataIC50: 550nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandPNGBDBM592304((2S)-1-{[2-(2-methylbiphenyl-3-yl)furo[2,3-b]pyrid...)
Affinity DataIC50: 550nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent