Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 11088
TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476583(US10869929, Compound 18 | US11554172, Compound 18)
Affinity DataIC50: 0.100nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM589245(US11554172, Compound 19)
Affinity DataIC50: 0.140nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM589230(US11554172, Compound Fluticasone-Propionate)
Affinity DataIC50: 0.150nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476575(US10869929, Compound 8 | US11554172, Compound 8)
Affinity DataIC50: 0.25nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476572(US10869929, Compound 6 | US11554172, Compound 6)
Affinity DataIC50: 0.320nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476567(US10869929, Compound 3 | US11554172, Compound 3)
Affinity DataIC50: 0.440nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476573(US10869929, Compound 7 | US11554172, Compound 7)
Affinity DataIC50: 0.450nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476568(US10869929, Compound 4 | US11554172, Compound 4)
Affinity DataIC50: 0.710nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50354850(BUDESONIDE | US10869929, Compound Budesonide | US1...)
Affinity DataIC50: 0.900nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476576(US10869929, Compound 9 | US11554172, Compound 9)
Affinity DataIC50: 1.67nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476577(US10869929, Compound 10 | US11554172, Compound 10)
Affinity DataIC50: 1.99nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476585(US10869929, Compound 27 | US11554172, Compound 27)
Affinity DataIC50: 2nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 2.10nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476591(US10869929, Compound 30 | US11554172, Compound 30)
Affinity DataIC50: 2.40nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476593(US10869929, Compound 31 | US11554172, Compound 31)
Affinity DataIC50: 3.90nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476589(US10869929, Compound 28 | US11554172, Compound 28)
Affinity DataIC50: 4.10nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476581(US10869929, Compound 14 | US11554172, Compound 14)
Affinity DataIC50: 18.1nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476590(US10869929, Compound 29 | US11554172, Compound 29)
Affinity DataIC50: 24.2nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476594(US10869929, Compound 32 | US11554172, Compound 32)
Affinity DataIC50: 115nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476569(US10869929, Compound 5 | US11554172, Compound 5)
Affinity DataIC50: 160nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476579(US10869929, Compound 12 | US11554172, Compound 12)
Affinity DataIC50: 162nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476580(US10869929, Compound 13 | US11554172, Compound 13)
Affinity DataIC50: 1.23E+3nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
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