Compile Data Set for Download or QSAR
Report error Found 289 Enz. Inhib. hit(s) with all data for entry = 11045
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587766(US11535621, Example 27)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
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TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587768((S)-2-(1H-Imidazol-1-yl)-N-(tetrahydro-2H-pyran-3-...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587779(2-(1H-Imidazol-1-yl)-N-((1s,4s)-4-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587780(2-(1H-Imidazol-1-yl)-N-((1s,4s)-4-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587798(US11535621, Example 58)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587799(US11535621, Example 59)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587803(US11535621, Example 63)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587815(US11535621, Example 75)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587817(US11535621, Example 77)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587822(US11535621, Example 81)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587823(US11535621, Example 82)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587824(US11535621, Example 83)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587825(US11535621, Example 84)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587826(US11535621, Example 85)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587827(US11535621, Example 86)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587828(US11535621, Example 87)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587829(US11535621, Example 88)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587830(US11535621, Example 89)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587831(US11535621, Example 90)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587832(US11535621, Example 91)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587833(US11535621, Example 92)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587835(US11535621, Example 94)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587837(US11535621, Example 96)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587839(US11535621, Example 98)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587840(US11535621, Example 99)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587841(US11535621, Example 100)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587845(US11535621, Example 104)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587848(US11535621, Example 107)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587850(US11535621, Example 109)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587855(N-((1r,4r)-4-(acetamidomethyl)cyclohexyl)-2-(1H-im...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587859(US11535621, Example 118)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587862(N-((1s,4s)-4-hydroxy-4-(trifluoromethyl)cyclohexyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587865(2-(1H-imidazol-1-yl)-N-((1r,4r)-4-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587866(US11535621, Example 122)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587877(2-(1H-imidazol-1-yl)-N-((1r,4r)-4-methoxy-4-methyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587880(US11535621, Example 130)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587881(US11535621, Example 131)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587882(US11535621, Example 132)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587884(US11535621, Example 134)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587886(US11535621, Example 136)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587887(US11535621, Example 137)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587888(US11535621, Example 138)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587890(US11535621, Example 140)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587891(US11535621, Example 141)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587892(US11535621, Example 142)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587894(US11535621, Example 144)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587895(US11535621, Example 145)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587898(US11535621, Example 148)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587899(US11535621, Example 149)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587900(US11535621, Example 150)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

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