Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 10998
TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582516(US11524956, Example 1)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582516(US11524956, Example 1)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
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TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582537(US11524956, Example 2 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582537(US11524956, Example 2 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582539(US11524956, Example 3 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582539(US11524956, Example 3 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582540(US11524956, Example 4 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582540(US11524956, Example 4 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582541(US11524956, Example 5 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582541(US11524956, Example 5 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582542(US11524956, Example 6 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582542(US11524956, Example 6 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582543(US11524956, Example 7 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM582543(US11524956, Example 7 | (E)-N-(4-(3-chloro-4-fluor...)
Affinity DataIC50: 100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent