Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 10988
TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582031(US11518759, Compound 4 | Preparation of pyrrolidin...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582032(US11518759, Compound 5 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582033(US11518759, Compound 6 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582035(US11518759, Compound 8 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582036(US11518759, Compound 9 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582028(US11518759, Compound 1)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582029(US11518759, Compound 2 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582030(US11518759, Compound 3 | Preparation of (2S,4R)-1-...)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582034(US11518759, Compound 7)
Affinity DataIC50: 550nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent