Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 10957
TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581007(US11492367, Compound 1)
Affinity DataKd:  120nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581008(US11492367, Compound 2)
Affinity DataKd:  120nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581019(US11492367, Compound 17)
Affinity DataKd:  4.85nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581030(US11492367, Compound 33)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581028(US11492367, Compound 31)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581026(US11492367, Compound 29)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581023(US11492367, Compound 26)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581020(US11492367, Compound 18)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581011(US11492367, Compound 7)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581027(US11492367, Compound 30)
Affinity DataIC50: 11nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581024(US11492367, Compound 27)
Affinity DataIC50: 24nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581029(US11492367, Compound 32)
Affinity DataIC50: 34nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581019(US11492367, Compound 17)
Affinity DataIC50: 38nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581018(US11492367, Compound 13)
Affinity DataIC50: 42nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581010(US11492367, Compound 6)
Affinity DataIC50: 61nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581025(US11492367, Compound 28)
Affinity DataIC50: 61nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581022(US11492367, Compound 25)
Affinity DataIC50: 85nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581017(US11492367, Compound 12)
Affinity DataIC50: 270nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581012(US11492367, Compound 8)
Affinity DataIC50: 270nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581014(US11492367, Compound 9)
Affinity DataIC50: 960nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581009(US11492367, Compound 5)
Affinity DataIC50: 1.83E+3nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581016(US11492367, Compound 11)
Affinity DataIC50: 2.46E+3nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581015(US11492367, Compound 10)
Affinity DataIC50: 6.69E+3nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581007(US11492367, Compound 1)
Affinity DataIC50: 7.31E+3nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM581019(US11492367, Compound 17)
Affinity DataIC50: 1.00E+4nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581008(US11492367, Compound 2)
Affinity DataIC50: 5.67E+4nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581021(US11492367, Compound 24)
Affinity DataIC50: 1.00E+5nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM581007(US11492367, Compound 1)
Affinity DataIC50: 2.00E+5nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent