Compile Data Set for Download or QSAR
Report error Found 403 Enz. Inhib. hit(s) with all data for entry = 10941
TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202656(CHEMBL3916438 | US10730889, Example 419 | US114857...)
Affinity DataIC50: 1.49nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202721(CHEMBL3968268 | US10730889, Example 399 | US114857...)
Affinity DataIC50: 3.31nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202644(CHEMBL3949594 | US10730889, Example 366 | US114857...)
Affinity DataIC50: 3.40nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202664(CHEMBL3925878 | US10730889, Example 408 | US114857...)
Affinity DataIC50: 3.76nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50: 4.32nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455760(BDBM50202668 | US10730889, Example 355 | N-[[6-(2,...)
Affinity DataIC50: 4.41nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202646(CHEMBL3889487 | US11485745, Example 290)
Affinity DataIC50: 4.54nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455612(US10730889, Example 200 | tert-butyl 2-[(1,3- dihy...)
Affinity DataIC50: 4.56nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455449(US10730889, Example 47 | N-[[6-(2-phenylacetyl)-6-...)
Affinity DataIC50: 4.59nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455813(N-[[(2S)-6-(3-methylbutanoyl)- 6-azaspiro[2.5]octa...)
Affinity DataIC50: 5.30nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202665(CHEMBL3984355 | US10730889, Example 418 | US114857...)
Affinity DataIC50: 5.60nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580463(US11485745, Example 356 | N-[[6-[2-(1,4-dimethyl-4...)
Affinity DataIC50: 6nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202636(CHEMBL3963163 | US10730889, Example 45 | US1148574...)
Affinity DataIC50: 6.23nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50: 6.36nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580507(US11485745, Example 405 | N-[[6-[4-(1-methyl-4- pi...)
Affinity DataIC50: 6.37nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50: 6.80nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202712(CHEMBL3902837 | US10730889, Example 2 | US11485745...)
Affinity DataIC50: 7.19nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455779((3-methyltetrahydrofuran-3-yl) 2-[(1,3-dihydropyrr...)
Affinity DataIC50: 8.88nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580119(US11485745, Example 3 | tert-butyl 2- [(imidazo[1,...)
Affinity DataIC50: 8.96nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202663(CHEMBL3921880 | US10730889, Example 44 | US1148574...)
Affinity DataIC50: 9.53nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580469(US11485745, Example 362 | N-[[6-[4-(4-methylpipera...)
Affinity DataIC50: 9.69nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202644(CHEMBL3949594 | US10730889, Example 366 | US114857...)
Affinity DataIC50: 9.93nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50: 9.96nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202716(CHEMBL3913883 | US11485745, Example 218)
Affinity DataIC50: 9.97nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455696(N-[[6-(2-phenoxyacetyl)-6- azaspiro[2.5]octan-2-yl...)
Affinity DataIC50: 9.99nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202663(CHEMBL3921880 | US10730889, Example 44 | US1148574...)
Affinity DataIC50: 10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580454(US11485745, Example 346 | N-[[6-[4-[(4-methylpiper...)
Affinity DataIC50: 10.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580505(US11485745, Example 403 | N-[[6-[2-[4-methyl-1-(2,...)
Affinity DataIC50: 11nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455430(US10730889, Example 29 | N-[[6-(3,3-dimethylbutano...)
Affinity DataIC50: 11.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580308(US11485745, Example 197 | N-[[6-(3-cyclohexylpropa...)
Affinity DataIC50: 11.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202714(CHEMBL3974268 | US10730889, Example 347 | US114857...)
Affinity DataIC50: 11.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202653(CHEMBL3913503 | US10730889, Example 409 | US114857...)
Affinity DataIC50: 11.9nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580313(US11485745, Example 202 | N-[[6-[2-[3- (trifluorom...)
Affinity DataIC50: 12nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455760(BDBM50202668 | US10730889, Example 355 | N-[[6-(2,...)
Affinity DataIC50: 12.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455799(N-[[6-[4- (trifluoromethyl]pyridine-3- carbonyl]-6...)
Affinity DataIC50: 12.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202664(CHEMBL3925878 | US10730889, Example 408 | US114857...)
Affinity DataIC50: 12.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455815(N-[[6-(4-methyloxazole-5- carbonyl)-6-azaspiro[2.5...)
Affinity DataIC50: 12.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455808(N-[[6-(2-pyrimidin-5-ylacetyl)- 6-azaspiro[2.5]oct...)
Affinity DataIC50: 13.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202638(CHEMBL3923552 | US10730889, Example 404 | US114857...)
Affinity DataIC50: 13.6nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455746(N-[[6-[4-(4-Methylpiperazin-1-yl)benzoyl]-6-azaspi...)
Affinity DataIC50: 13.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202641(CHEMBL3930818 | US10730889, Example 42 | US1148574...)
Affinity DataIC50: 14.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580307(US11485745, Example 196 | N-[[6-(2-cyclohexylacety...)
Affinity DataIC50: 14.4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580310(US11485745, Example 199 | N-[[6-(3-phenylpropanoyl...)
Affinity DataIC50: 14.4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580404(US11485745, Example 295 | N-[[6-(1-benzyl-3,5-dime...)
Affinity DataIC50: 14.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202669(CHEMBL3939767 | US10730889, Example 151 | US114857...)
Affinity DataIC50: 14.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455792(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50: 14.9nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50202670(CHEMBL3904503 | US10730889, Example 219 | US114857...)
Affinity DataIC50: 15.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580389(US11485745, Example 280 | N-[[6-[4-(2-methyltetraz...)
Affinity DataIC50: 15.2nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455776(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50: 15.2nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM455718(N-[[6-(5-methylimidazo[1,2- a]pyridine-2-carbonyl)...)
Affinity DataIC50: 15.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
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