Compile Data Set for Download or QSAR
Report error Found 223 Enz. Inhib. hit(s) with all data for entry = 10923
Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578482(US11479539, Compound 1)
Affinity DataEC50:  408nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578483(US11479539, Compound 2)
Affinity DataEC50:  228nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578484(US11479539, Compound 3)
Affinity DataEC50:  424nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578485(US11479539, Compound 4)
Affinity DataEC50:  1.14E+3nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578486(US11479539, Compound 5 | US11479539, Compound 124)
Affinity DataEC50:  10nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578487(US11479539, Compound 6)
Affinity DataEC50: >1.00E+4nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578488(US11479539, Compound 7)
Affinity DataEC50:  82nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578489(US11479539, Compound 8)
Affinity DataEC50:  186nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578490(US11479539, Compound 9)
Affinity DataEC50:  269nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578491(US11479539, Compound 10)
Affinity DataEC50: >3.00E+4nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578492(US11479539, Compound 11)
Affinity DataEC50:  85nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578493(US11479539, Compound 12)
Affinity DataEC50:  119nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578494(US11479539, Compound 13)
Affinity DataEC50:  1.00E+4nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578495(US11479539, Compound 14 | US11479539, Compound 111...)
Affinity DataEC50:  12nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM50502724(CHEMBL4463989 | US11479539, Compound 122)
Affinity DataEC50:  24nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578497(US11479539, Compound 16)
Affinity DataEC50:  660nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578498(US11479539, Compound 17)
Affinity DataEC50:  309nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578499(US11479539, Compound 18)
Affinity DataEC50:  265nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578500(US11479539, Compound 19)
Affinity DataEC50:  1.24E+3nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578501(US11479539, Compound 20)
Affinity DataEC50:  126nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578502(US11479539, Compound 21)
Affinity DataEC50:  452nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578503(US11479539, Compound 22)
Affinity DataEC50:  45nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM50502729(CHEMBL4593124 | US11479539, Compound 23)
Affinity DataEC50:  56nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578505(US11479539, Compound 24)
Affinity DataEC50: >1.00E+4nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578506(US11479539, Compound 25)
Affinity DataEC50:  70nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578507(US11479539, Compound 26 | 3-(5-fluoro-3- (trifluor...)
Affinity DataEC50:  24nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578508(US11479539, Compound 27 | US11479539, Compound 123...)
Affinity DataEC50:  180nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578509(US11479539, Compound 28 | US11479539, Compound 44 ...)
Affinity DataEC50:  36nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578510(US11479539, Compound 29 | 3-(2,6- dimethylpyridin-...)
Affinity DataEC50:  91nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578511(US11479539, Compound 30 | 3-methoxy-5,5- dimethyl-...)
Affinity DataEC50:  458nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578512(US11479539, Compound 31 | 3-(5-fluoro-3- methylpyr...)
Affinity DataEC50:  19nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578513(US11479539, Compound 32 | 3-(5- chloropyridin-2- y...)
Affinity DataEC50:  55nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578514(US11479539, Compound 33 | US11479539, Compound 141...)
Affinity DataEC50:  383nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578515(US11479539, Compound 34 | US11479539, Compound 139...)
Affinity DataEC50:  12nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578516(US11479539, Compound 35 | US11479539, Compound 143...)
Affinity DataEC50:  39nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578517(US11479539, Compound 36 | US11479539, Compound 142...)
Affinity DataEC50:  96nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578518(US11479539, Compound 37 | 3-ethoxy-3-(5- fluoropyr...)
Affinity DataEC50:  86nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578519(US11479539, Compound 38 | (S)-3-methoxy- 5,5-dimet...)
Affinity DataEC50:  132nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578520(US11479539, Compound 39 | US11479539, Compound 144...)
Affinity DataEC50:  125nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578521(US11479539, Compound 40 | (S)-3-methoxy- 5,5-dimet...)
Affinity DataEC50:  38nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578522(US11479539, Compound 41 | US11479539, Compound 147...)
Affinity DataEC50:  11nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM50502734(CHEMBL4442320 | US11479539, Compound 42)
Affinity DataEC50:  33nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578524(US11479539, Compound 43 | 3-methoxy-5,5- dimethyl-...)
Affinity DataEC50:  129nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578509(US11479539, Compound 28 | US11479539, Compound 44 ...)
Affinity DataEC50:  37nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578526(US11479539, Compound 45 | US11479539, Compound 158...)
Affinity DataEC50:  28nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578527(US11479539, Compound 46 | 3-(2,4- dimethylthiazol-...)
Affinity DataEC50:  304nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM50502728(CHEMBL4542755 | US11479539, Compound 174)
Affinity DataEC50:  8nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM50502727(CHEMBL4584154 | US11479539, Compound 48)
Affinity DataEC50:  6nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578530(US11479539, Compound 49 | US11479539, Compound 126)
Affinity DataEC50:  138nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578531(US11479539, Compound 50 | US11479539, Compound 128...)
Affinity DataEC50:  30nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

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