Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 10747
TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM563327(US11407750, Compound 3)
Affinity DataIC50: 55nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM563327(US11407750, Compound 3)
Affinity DataIC50: 55nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM563327(US11407750, Compound 3)
Affinity DataIC50: 300nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent