Compile Data Set for Download or QSAR
Report error Found 165 Enz. Inhib. hit(s) with all data for entry = 10695
TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560274(US11377439, Example 111)
Affinity DataIC50: 3nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560238(US11377439, Example 75)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560251(US11377439, Example 88)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560256(US11377439, Example 93)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560266(US11377439, Example 103)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560270(US11377439, Example 107)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560273(US11377439, Example 110)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560275(US11377439, Example 112)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560276(US11377439, Example 113)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560277(US11377439, Example 114)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560279(US11377439, Example 116)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560137(US11377439, Example 15)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560239(US11377439, Example 76)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560246(US11377439, Example 83)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560255(US11377439, Example 92)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560258(US11377439, Example 95)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560261(US11377439, Example 98)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560262(US11377439, Example 99)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560281(US11377439, Example 118)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560299(US11377439, Example 136)
Affinity DataIC50: 5nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560132(US11377439, Example 14)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560259(US11377439, Example 96)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560260(US11377439, Example 97)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
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TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560263(US11377439, Example 100)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560264(US11377439, Example 101)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560265(US11377439, Example 102)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560269(US11377439, Example 106)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560301(US11377439, Example 138)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560303(US11377439, Example 140)
Affinity DataIC50: 6nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560242(US11377439, Example 79)
Affinity DataIC50: 7nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560244(US11377439, Example 81)
Affinity DataIC50: 7nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560245(US11377439, Example 82)
Affinity DataIC50: 7nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560271(US11377439, Example 108)
Affinity DataIC50: 7nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560284(US11377439, Example 121)
Affinity DataIC50: 7nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560202(US11377439, Example 39)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560252(US11377439, Example 89)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560272(US11377439, Example 109)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560278(US11377439, Example 115)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560290(US11377439, Example 127)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560295(US11377439, Example 132)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560296(US11377439, Example 133)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560298(US11377439, Example 135)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560307(US11377439, Example 144)
Affinity DataIC50: 8nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560237(US11377439, Example 74)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560240(US11377439, Example 77)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560250(US11377439, Example 87)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560254(US11377439, Example 91)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560257(US11377439, Example 94)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560267(US11377439, Example 104)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560268(US11377439, Example 105)
Affinity DataIC50: 9nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent

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