Compile Data Set for Download or QSAR
Report error Found 128 Enz. Inhib. hit(s) with all data for entry = 10675
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)
Affinity DataIC50: 41nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558862(US11370770, Compound 6n)
Affinity DataIC50: 60nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558880(US11370770, Compound 6ee)
Affinity DataIC50: 63nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)
Affinity DataIC50: 66nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558875(US11370770, Compound 6z)
Affinity DataIC50: 100nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)
Affinity DataIC50: 100nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558864(US11370770, Compound 6p)
Affinity DataIC50: 110nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558878(US11370770, Compound 6cc)
Affinity DataIC50: 120nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558862(US11370770, Compound 6n)
Affinity DataIC50: 130nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558867(US11370770, Compound 6s)
Affinity DataIC50: 150nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558848(US11370770, Compound 6a)
Affinity DataIC50: 180nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558867(US11370770, Compound 6s)
Affinity DataIC50: 180nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558866(US11370770, Compound 6r)
Affinity DataIC50: 200nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558865(US11370770, Compound 6q)
Affinity DataIC50: 210nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558867(US11370770, Compound 6s)
Affinity DataIC50: 220nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558858(US11370770, Compound 6j)
Affinity DataIC50: 240nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558858(US11370770, Compound 6j)
Affinity DataIC50: 250nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558880(US11370770, Compound 6ee)
Affinity DataIC50: 260nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Northwestern University

US Patent
LigandPNGBDBM558875(US11370770, Compound 6z)
Affinity DataIC50: 350nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558875(US11370770, Compound 6z)
Affinity DataIC50: 360nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558863(US11370770, Compound 6o)
Affinity DataIC50: 390nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558864(US11370770, Compound 6p)
Affinity DataIC50: 410nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558865(US11370770, Compound 6q)
Affinity DataIC50: 410nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558879(US11370770, Compound 6dd)
Affinity DataIC50: 420nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558876(US11370770, Compound 6aa)
Affinity DataIC50: 460nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558848(US11370770, Compound 6a)
Affinity DataIC50: 460nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558862(US11370770, Compound 6n)
Affinity DataIC50: 470nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558866(US11370770, Compound 6r)
Affinity DataIC50: 510nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558866(US11370770, Compound 6r)
Affinity DataIC50: 560nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558864(US11370770, Compound 6p)
Affinity DataIC50: 560nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558865(US11370770, Compound 6q)
Affinity DataIC50: 590nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558848(US11370770, Compound 6a)
Affinity DataIC50: 640nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558875(US11370770, Compound 6z)
Affinity DataIC50: 720nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558863(US11370770, Compound 6o)
Affinity DataIC50: 750nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558858(US11370770, Compound 6j)
Affinity DataIC50: 760nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558850(US11370770, Compound 6b)
Affinity DataIC50: 880nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558850(US11370770, Compound 6b)
Affinity DataIC50: 920nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558870(US11370770, Compound 6v)
Affinity DataIC50: 970nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558863(US11370770, Compound 6o)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558861(US11370770, Compound 6m)
Affinity DataIC50: 1.10E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM50053313(CHEMBL3330241 | US11370770, Compound 6h)
Affinity DataIC50: 1.30E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558872(US11370770, Compound 6w)
Affinity DataIC50: 1.30E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558869(US11370770, Compound 6u)
Affinity DataIC50: 1.40E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558880(US11370770, Compound 6ee)
Affinity DataIC50: 1.50E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558868(US11370770, Compound 6t)
Affinity DataIC50: 1.60E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Northwestern University

US Patent
LigandPNGBDBM558858(US11370770, Compound 6j)
Affinity DataIC50: 1.60E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 7(Human)
Northwestern University

US Patent
LigandPNGBDBM558862(US11370770, Compound 6n)
Affinity DataIC50: 2.00E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Northwestern University

US Patent
LigandPNGBDBM558866(US11370770, Compound 6r)
Affinity DataIC50: 2.10E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM558877(US11370770, Compound 6bb)
Affinity DataIC50: 2.20E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 7(Human)
Northwestern University

US Patent
LigandPNGBDBM558858(US11370770, Compound 6j)
Affinity DataIC50: 2.20E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

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